Studies on Cancerocidal Substances. XVI. Some Sulfonic Acid Esters as Anti-cancer Agents.

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概要

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• A number of sulfonic acid esters were prepared and the relation between their thiosulfate up-take in vitro and their antimitotic activity on proliferating cells of the Yoshida sarcoma was discussed. It was found that these esters acted in a similar manner both in chemical and in biological actions as nitrogen mustard.

• 公益社団法人日本薬学会の論文

著者

• 桜井 欽夫

  Cancer Institute Japanese Foundation For Cancer Research

• 桜井 欽夫

  Iatrochemical Institute Of The Pharmacological Research Foundation Tokyo

• 石館 守三

  Iatrochemical Institute of Pharmacological Research Foundation

• 尾張 栄彦

  Iatrochemical Institute of the Pharmacological Research Foundation

関連論文

• Bacteriostatic Activity of the Nitrogen Mustard N-Oxides against Escherichia coli
• N-Oxides of β-Chloroethylamine Derivatives.
• Studies on Carcinostatic Substances. XLI. Preparation of Azide Derivatives of 1,1-Bis (2-chloroethyl) hydrazine.
• The Effect of Anti-tumor Agents on the Dehydrogenase Activity of Tumors.
• Studies on Carcinostatic Substances. XXXII. : Acquired Resistance of Yoshida Sarcoma by Treatment with Derivatives of Nitrogen Mustard.
• Studies on Carcinostatic Substances. XXVII. Anti-tumor Activity of 2-Chloroethylamine Derivatives on the in vitro-Cultured Yoshida Sarcoma Cells
• Studies on Carcinostatic Substances. XXII. Screening Method for Antimitotic Substance using the in vitro-Cultured Yoshida Sarcoma Cells.
• Studies on Carcinostatic Substances. XX. Studies on the Culture of Yoshida Sarcoma Cells in vitro.
• Synthesis and Evaluation of the Anticancer Activity of a New Series of Methanesulfonates
• Synthesis and Evaluation of the Anticancer Activity of Some Water Soluble Maleimide Derivatives
• Fatty Acid Components of Lipid Fractions of Yoshida Sarcoma and Rat Ascites Hepatomas
• Carcinostatic Activity of Several New Derivatives of Sulfonic Acid esters of Some Aminoglycols
• Preparation of Derivatives of Nitrogen Mustard having Structure of α-Amino Acid Amide
• Carcinostatic Methanesulfonic Acid Esters of Some Aminoglycols
• Carcinostatic Methanesulfonic Acid Esters of Nitrogen Mustard Analogs
• Studies on Carcinostatic Substances. XXXVII. Preparation of Derivatives of Nitrogen Mustard having Metal Chelate-forming Activity.
• Studies on Carcinostatic Substances. XXXVI. A New Type of Antitumor Derivatives of Nitrogen Mustard with Latent Activity.
• Studies on Carcinostatic Substances. XXXIV. Anti-tumor Activity of 2,2-Bis (2-chloroethyl) isoxazolidinium Chloride and Related Compounds.
• Studies on Carcinostatic Substances. XXX. Syntheses of Derivatives of Nitrogen Mustard related to Amino Acid.
• Paper Chromatographic Detection of Nitrogen Mustard
• Studies on Carcinostatic Substances. XXIX. 1,1-Bis(2-chloroethyl)-hydrazine and its Derivatives as Tumor-inhibiting Agent
• Studies on Carcinostatic Substances. XXVI. Preparation of Bis(2-chloroethyl)amine Derivatives and Related N-Oxides.
• Studies on Carcinostatic Substances. XXIV. Preparation of Diphenylphosphoric Acid Esters of N-Methyl-and N-Phenyl-bis(2-hydroxyethyl)amine and their Alkylating Activity.
• Studies on Carcinostatic Substances. XXIII. Correlation between Anti-tumor and leucopenia-inducing Effects of Alkylating Agents
• 1,1-Bis (2-chloroethyl) hydrazine and its Antitumor Activity
• Studies on Carcinostatic Substances. XIX. The Preparation and Properties of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamine N, N'-Dioxides.
• Studies on Carcinostatic Substances. XVIII. Anticancer Action of N, N'-Bis (2-chloroethyl)-N, N'-dimethylpolymethylenediamines.
• Studies on Cancerocidal Substances. XVII. Reaction of Nitrogen Mustard N-Oxides and Amino Acid.
• Studies on Cancerocidal Substances. XVI. Some Sulfonic Acid Esters as Anti-cancer Agents.
• Studies on Cancerocidal Substances. XV. Preparation of Some New Azo Derivatives of Bis (β-chloroethyl) amine.
• 制癌性物質の研究(第14報)Bis(β-chloroethyl)amine及びそのN-Oxide類の合成
• Transformation Reaction of Nitrogen Mustard N-Oxides in Aqeous Solution
• Effect of α, β-Diphenylethylamines upon Yoshida Sarcoma.

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