Bioconversion of Cardiac Aglycones by Gibberella saubinettii (MONT.) SACC
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概要
- 論文の詳細を見る
Bioconversions of several cardiac aglycones by a strain of Gibberella saubinettii (MONT.) SACC. were repoted. Digitoxigenin was converted to digoxigenin in a good yield. Digitoxigenone was transformed into 3-dehydrodigoxigenin, 3-epidigitoxigenin, and 3-epidigoxigenin. Diginatigenin was obtained in approximately 6% yield from gitoxigenin. Oleandrigenin gave 16-monoacetyldiginatigenin (ca. 15% yield) and diginatigenin (ca. 2%yield), but the formation of gitoxigenin from oleandrigenin by incubation was found to be quite small. Enzymatic hydrolysis of 16β-acetoxyl group of the cardenolide was discussed.
- 公益社団法人日本薬学会の論文
- 1960-06-25
著者
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石館 守三
Faculty of Pharmaceutical Sciences, University of Tokyo
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山田 厚
Tokyo Biochemical Research Institute
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石館 守三
笹川記念保健協力財団
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山田 厚
Iatrochemical Institute Of Pharmacological Research Foundation
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岡田 正志
(財)東京生化学研究会
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岡田 正志
Iatrochemical Institute of Pharmacological Research Foundation
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石館 守三
Faculty Of Pharmaceutical Sciences University Of Tokyo
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