オルトフェニルフェノールのEscherichia coli-ファージ系およびBacillus subtilis-ファージ系に対する作用

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We had found that o-phenylphenol (OPP) induced marked premature lysis of phage-infected cells in the Lactobacillus casei-phage J1 system.This paper describes the effects of OPP on Escherichia coli-phage systems (T1,T3,T4,T5,and φ×174) and bacillus subtilis-phage systems (M2 and SPO1). OPP was bactericidal at 8-10×10^<-4>M. At these concentrations, it did not affect the infectivity of free phages or adsorption of phages onto host cells. It inhibited the growth of phages.The number of infective centers decreased with T4,T5,M2,and SPO1,but not with T1,T3,and φ×174.OPP induced moderate premature lysis of cells infected with T4 and T5,while it inhibited the lysis of cells infected with T1,T3,and φ×174. It induced mild lysis of cells infected with M2 and SPO1,but this was not specific for phage-infected cells.
社団法人日本生物工学会の論文
1989-05-25