低級脂肪酸モノグリセリドのLactobacillus casei-J1ファージ系に対する作用

概要

論文の詳細を見る
Effects of monoglycerides of lower fatty acid(monocaprylin and monocaprin)on a Lactobacillus casei-phage J1 system were investigated as a part of the basic study of the phage control in lactic fermentations.The monoglycerides were bacterecidal, but not bacteriolytic toward normal cells. They did not affect the infectivity of a free phage, the adsorption of the phage onto cells, or the injection of phage DNA into cells even at high concentrations. They completely inhibited the growth of the phage at their bactericidal concentrations. They induced premature lysis of phage-infected cells; thus the infective center was lost and no new phage was reproduced.The addition of the monoglycerides at any time during the latent period also induced premature lysis. The monoglycerides could be used as a new lysing agent for phage-infected cells.
社団法人日本生物工学会の論文