Myrsinoic Acid E, an Anti-inflammatory Compound from Myrsine seguinii(Organic Chemistry)
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概要
- 論文の詳細を見る
The methanolic extract of Myrsine seguinii yielded the novel anti-inflammatory compound, myrsinoic acid E (1), whose structure was elucidated to be 3, 5-diger-anyl-4-hydroxy benzoic acid. We synthesized 1- and its 3, 5-diprenyl (2) and 3, 5-difarnesyl analogues (3). Compounds 1-3 suppressed 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation of mouse ears by 59%, 14%, and 69% at a dose of 1.4 μmol.
- 社団法人日本農芸化学会の論文
- 2003-09-23
著者
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HIROTA Mitsuru
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
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Hirose Masao
国立医薬品食品衛生研究所 病理
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Makita Hiroki
岐阜大学 第1病理
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Hirota M
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
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Hirota Mitsuru
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
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Makabe Hidefumi
Science of Functional Foods, Graduate School of Agriculture, Shinshu University
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Makabe H
Shinshu Univ. Nagano Jpn
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Kamo Tsunashi
Biodiversity Division National Institute For Agro-environmental Sciences:department Of Bioscience An
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Kamo Tsunashi
Crest Japan Science And Technology Corporation (jst):division Of Applied Life Science Graduate Schoo
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KAMO Tsunashi
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
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MIYAZAKI Shintaro
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
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Miyazaki Shintaro
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
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