Anti-inflammatory Cyathane Diterpenoids from Sarcodon scabrosus

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概要

• 論文の詳細を見る

• Four novel diterpenoids were isolated from the fruiting bodies of Sarcodon scabrosus (Fr.) Karst. (Boraginaceae) together with neosarcodonin A. One of the novel compounds was elucidated to be a cyathane diterpenoid, namely neosarcodonin O, by its spectral data. The others were characterized as 19-O-linoleoyl, 19-O-oleoyl and 19-O-stearoyl derivatives of sarcodonin A, after comparison with the authentic samples synthetically prepared from sarcodonin A. These compounds, together with the five 19-O-acyl derivatives synthesized from sarcodonin A, each exhibited inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation on mouse ears by topical application.

• 社団法人 日本農芸化学会の論文
• 2004-06-23

著者

• HIROTA Mitsuru

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Makita Hiroki

  岐阜大学 第1病理

• Hirose Masao

  Division Of Pathology National Institute Of Health Sciences

• Hirota M

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

• Hirota Mitsuru

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

• IMURA Yuki

  Department of Gynecology, Tokyu General Hospital

• Shibata Hiroyuki

  Institute For Chemical Research Kyoto University

• Imura Yuki

  Department Of Applied Biological Chemistry School Of Agricultural And Life Science The University Of

• Makabe Hidefumi

  Science of Functional Foods, Graduate School of Agriculture, Shinshu University

• Makabe H

  Shinshu Univ. Nagano Jpn

• Shibata Hisao

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Hirose Masao

  Department Of Pathology Nagoya Higashi Municipal Hospital

• Shibata H

  Dept. Life Environ. Sci. Shimane Univ.

• Shibata Hisao

  Department Of Agricultural Chemistry Faculty Of Agricultural Shinshu University

• Kamo Tsunashi

  Biodiversity Division National Institute For Agro-environmental Sciences:department Of Bioscience An

• Kamo Tsunashi

  Crest Japan Science And Technology Corporation (jst):division Of Applied Life Science Graduate Schoo

• KAMO Tsunashi

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Mori Hideki

  First Department Of Pathology Gifu University School Of Medicine

• HAGIO Tomomi

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Hagio Tomomi

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

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