A Tyrosinase Inhibitor, Daedalin A, from Mycelial Culture of Daedalea dickinsii

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概要

• 論文の詳細を見る

• A chromene-type compound, daedalin A (1), was isolated from mycelial culture broth of Daedalea dickinsii. Based on spectroscopic data, the structure of 1 was found to be (2R)-6-hydroxy-2-hydroxymethyl-2-methyl-2H-chromene. Daedalin A (1) strongly inhibited the activity of tyrosinase (IC50: 194 μM). In addition, 1 also showed 1,1-diphenyl-2-picrylhydrazyl scavenging activity (IC50: 16.9 μM) and superoxide anion scavenging activity (IC50: 28.5 μM).

• 社団法人 日本農芸化学会の論文
• 2007-11-23

著者

• HIROTA Mitsuru

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Mori H

  Division Of Pathology National Institute Of Health Sciences

• Hirose Masao

  国立医薬品食品衛生研究所 病理

• Hirose M

  Division Of Pathology National Institute Of Health Sciences:food Safety Commission

• Hirose Masao

  国立医薬品食品衛生研究所 病理部

• Hirose Masao

  名古屋市立大学 医学研究科実験病態病理学

• Mori Hideki

  岐阜薬科大学 生物薬学研究所

• Makita Hiroki

  岐阜大学 第1病理

• Hirose Masao

  Division Of Pathology National Institute Of Health Sciences

• Hirose Masao

  Div. Pathol. Natl. Inst. Htlh. Sci.

• Hirota M

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

• Hirota Mitsuru

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

• Hosono M

  Aburahi Laboratories Shionogi Research Laboratories Shionogi Co Ltd.

• Makabe Hidefumi

  Science of Functional Foods, Graduate School of Agriculture, Shinshu University

• Makabe H

  Shinshu Univ. Nagano Jpn

• Mori Hideki

  College Of Engineering Graduate School Of Osaka Prefecture University

• Kamo Tsunashi

  Biodiversity Division National Institute For Agro-environmental Sciences:department Of Bioscience An

• Kamo Tsunashi

  Crest Japan Science And Technology Corporation (jst):division Of Applied Life Science Graduate Schoo

• KAMO Tsunashi

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• Mori Hideki

  First Department Of Pathology Gifu University School Of Medicine

• MORIMURA Keiji

  Interdisciplinary Graduate School of Science and Technology, Shinshu University

• YAMAZAKI Chihiro

  Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University

• HATTORI Yasunao

  Interdisciplinary Graduate School of Science and Technology, Shinshu University

• Yamazaki Chihiro

  Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University

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