Efficient Synthesis of Akolactone A via Pd-Catalyzed Carbonylation(Organic Chemistry)
スポンサーリンク
概要
- 論文の詳細を見る
The first synthesis of (+)- and (-)-akolactone A is described by using Pd-catalyzed carbonylation. A comparison of the optical rotation of both enantiomers of akolactone A and the natural compound suggests that the absolute configuration at the 4-position of akolactone A is R.
- 社団法人日本農芸化学会の論文
- 2003-12-23
著者
-
HIROTA Mitsuru
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
-
Makita Hiroki
岐阜大学 第1病理
-
KONNO HIROYUKI
Department of Surgery II, Hamamatsu University School of Medicine
-
Hirota M
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
-
Hirota Mitsuru
Department Of Bioscience And Biotechnology Faculty Of Agriculture Shinshu University
-
Konno Hiroyuki
Department Of Applied Biological Chemistry Faculty Of Agriculture
-
Makabe Hidefumi
Science of Functional Foods, Graduate School of Agriculture, Shinshu University
-
Makabe H
Shinshu Univ. Nagano Jpn
-
Hirose Masao
Department Of Pathology Nagoya Higashi Municipal Hospital
-
Konno Hiroyuki
Department Of Biological Science And Technology Faculty Of Engineering University Of Tokushima
-
Kan T
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Tokushima Bunri University
-
Kamo Tsunashi
Biodiversity Division National Institute For Agro-environmental Sciences:department Of Bioscience An
-
Kamo Tsunashi
Crest Japan Science And Technology Corporation (jst):division Of Applied Life Science Graduate Schoo
-
OKAJIMA Motonori
Sciences of Functional Foods, Graduate School of Agriculture, Shinshu University
-
KAMO Tsunashi
Department of Bioscience and Biotechnology, Faculty of Agriculture, Shinshu University
-
Mori Hideki
First Department Of Pathology Gifu University School Of Medicine
-
Okajima Motonori
Sciences Of Functional Foods Graduate School Of Agriculture Shinshu University
関連論文
- Biosynthetic origin of the nitrogen atom in cyanamide in Vicia villosa subsp. varia(Soil Chemistry and Soil Mineralogy)
- A 55-week chronic toxicity study of dietary administered kojic acid (KA) in male F344 rats
- Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide
- Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats
- Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation
- Inhibitory Effects of Octreotide Acetate, a Somatostatin Analog, on Spontaneous Chronic Pancreatitis in WBN/Kob Rats
- Rapid Screening for Chemopreventive Agents in Herbal Extracts in a PhIP Rat Model with DNA Adduct and Cell Proliferation as End-Points
- DNA Adduct Formation, Nucleolar Segregation and Cell Proliferation in Rats Treated with 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
- Depression of T cell-mediated immunity reduces sulfadimethoxine-induced capsular inflammation and inhibits associated development of invasive thyroid follicular cell carcinomas in rats
- Lack of enhancement of susceptibility to mammary and thyroid carcinogenesis in rats exposed to DMBA and DHPN following prepubertal iodine deficiency
- Modification by curcumin of mutagenic activation of carcinogenic N-nitrosamines by extrahepatic cytochromes P-450 2B1 and 2E1 in rats
- In vivo mutagenicity and initiation following oxidative DNA lesion in the kidneys of rats given potassium bromate
- Dose-dependent promotion of rat forestomach carcinogenesis by combined treatment with sodium nitrite and ascorbic acid after initiation with N-methyl-N'-nitro-N-nitrosoguanidine : Possible contribution of nitric oxide-associated oxidative DNA damage
- Comparison of enhancing effects of different goitrogen treatments in combination with β-estradiol-3-benzoate for establishing a rat two-stage thyroid carcinogenesis model to detect modifying effects of estrogenic compounds
- In vivo mutagenicity and oxidative DNA damage in the livers of gpt delta mice treated with flumequine(Mutagenicity, Carcinogenicity, Proceedings of the 32nd Annual Meeting)
- Catechol enhanced mice hepatotoxicity treated with acetaminophen(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)
- Lack of Modifying Effects of Combined Treatment of t-butylhydroquinone and Sodium Nitrite on Forestomach Carcinogenesis in rasH2 Mice Initiated with N-ethyl-N-nitrosourea
- Lack of Initiating Activity of Kojic Acid on Hepatocarcinogenesis in F344 Rats
- Electron Microscopical Evidence of the Protective Function of Thioredoxin (TRX/ADF) Transgene against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced Cellular Toxicity in the Liver and Brain
- Tumorigenic Susceptibility of Catechol on the Gastric Mucosa in rasH2 Mice
- P8-27 Susceptibility to pentachlorophenol, a mouse liver carcinogen in Nrf2-deficient mice(CIRCULATORY SYSTEM-2/ACTIVE OXYGEN)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Lack of Modifying Effect of Glycerol in Pulmonary Carcinogenesis in rasH2 Mice Induced by Urethane or 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
- Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
- P7-44 Toxicity Evaluation of Bt protein with 28-days dietary administration to gastric-acid reduced rat models(GENERAL TOXICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- P6-43 Screening of chemopreventive agents using a medium-term pancreas carcinogenesis model in hamsters(DRUG METABOLISM/CARCINOGENICITY)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Histological and immunohistochemical observations of mucin-depleted foci (MDF) stained with Alcian blue, in rat colon carcinogenesis induced with 1, 2-dimethylhydrazine dihydrochloride
- Dose-related changes of oxidative stress and cell proliferation in kidneys of male and female F344 rats exposed to potassium bromate
- Tumor formation is correlated with expression of β-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice
- A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate
- Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl) nitrosamine in rats after initiation
- Modulatory effects of hepatic, renal or thyroidal impairments on amitrole-induced thyroid carcinogenesis in rats pretreated with DHPN (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Inhibiting Effects of Ethinylestradiol on N-ethyl-M-nitrosourea-Initiated Uterine Carcinogenesis in Transgenic Mice Carrying a Human Prototype C-Ha-ras Gene (rasH2 mice) (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th A
- A possible role of oxidative stress in potassium bromate (KBrO_3) carcinogenesis (ACTIVE OXYGEN) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Safety evaluetion of Bt protein by dietary administration to a gastro-intestinal impairment rat model (GENERAL TOXICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Promoting Effects of Ethinylestradiol but not Atrazine on N-ethyl-N-nitrosourea-induced Uterine Carcinogenesis in ICR Mice
- Inhibitory effects of troglitazone, a peroxisome proliferator-activated receptor γ ligand, in rat tongue carcinogenesis initiated with 4-nitroquinoline 1-oxide
- Synergistic interaction between excess caffeine and deficient iodine on the promotion of thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl) nitrosamine
- Modifying Effects of 2,6-Dimethylaniline on Nasal Carcinogenesis in RasH2 Mice Initiated with 4-Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Lack of Modifying Effects of 2,6-Dimethylaniline on Lung Carcinogenesis in Transgenic Mice Carrying Human Prototype c-Ha-ras Gene Initiated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone
- Carcinoid tumor in the female urethral orifice : Rare case report and a review of the literature
- Difference in the Types of Uterine Tumors between Heterozygous p53-deficient and Wild Type CBA Mice Treated with Ethinylestradiol after N-ethyl-N-nitrosourea Initiation
- Modifying effect of atrazine on DMBA-induced mammary carcinogenesis in ovariectomized rats.(GENERAL SESSION BY POSTER PRESENTATION)(CARCINOGENICITY)
- Lung as a new target in rats of 2-amino-3-methylimidazo[4,5-f]quinoline carcinogenesis : Results of a two-stage model initiated with N-bis(2-hydroxypropyl)nitrosamine
- A Repeated 28 Days Oral Dose Toxicity Study of Genistein in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.(GENERAL SESSION BY POSTER PRESENTATION)(ENDOCRINE SYSTEM)
- The Mouse rasH2/BHT Model as an in vivo Rapid Assay for Lung Carcinogens
- Induction of Apoptosis by Sulindac in Azoxymethane-induced Possible Colonic Premaligmant Lesions in Rats
- Chemopreventive Effects of a Flavonoid Antioxidant Silymarin on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Urinary Bladder Carcinogenesis in Male ICR Mice
- Enhancement by Cigarette Smoke Exposure of 2-Amino-3,8-dimethylimidazo [4,5-f] quinoxaline-induced Rat Hepatocarcinogenesis in Close Association with Elevation of Hepatic CYP1A2
- P10-09 A Repeated 28 Days Oral Dose Toxicity Study of Methoxychlor in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.
- A Repeated 28 Days Oral Dose Toxicity Study of Genistein in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.(GENERAL SESSION BY POSTER PRESENTATION)(ENDOCRINE SYSTEM)
- P10-09 A Repeated 28 Days Oral Dose Toxicity Study of Methoxychlor in Rats, Based on the 'Enhanced OECD Test Guideline 407' for Screening Endocrine-disrupting Chemicals.
- Chemopreventive Effects of Scordinin on Diethylnitrosamine and Phenobarbital-induced Hepatocarcinogenesis in Male F344 Rats
- Dietary Prevention of Azoxymethane-Induced Colon Carcinogenesis with Rice-Germ in F344 Rats.
- Suppression of N-Nitrosomethylbenzylamine-induced Rat Esophageal Tumorigenesis by Dietary Feeding of 1'-Acetoxychavicol Acetate
- Suppression of Occurrence and Advancement of β-Catenin-accumulated Crypts, Possible Premalignant Lesions of Colon Cancer, by Selective Cyclooxygenase-2 Inhibitor, Celecoxib
- Chemopreventive Effect of Curcumin on N-Nitrosomethylbenzylamine-induced Esophageal Carcinogenesis in Rats
- Effect of Cigarette Smoke on the Mutagenic Activation of Environmental Carcinogens by Rodent Liver.
- Involvement of Lipid Peroxidation in Spontaneous Pancreatitis in WBN/Kob Rats
- Modifying Effects of a Flavonoid Morin on Azoxymethane-Induced Large Bowel Tumorigenesis in Rats.
- Chemopreventive Effect of Dietary Flavonoid Morin on Chemically Induced Rat Tongue Carcinogenesis.
- Esophageal Intramural Pseudodiverticulosis with Mallory-Weiss Syndrome : Report of a Case
- Gastrojejunocolic Fistula After Gastrectomy with Billroth II Reconstruction : Report of a Case
- Huge Cystic Lymphangioma of the Pancreas : Report of a Case
- Effect of Combination Therapy with Matrix Metalloproteinase Inhibitor MMI-166 and Mitomycin C on the Growth and Liver Metastasis of Human Colon Cancer
- Urokinase Receptor and Vascular Endothelial Growth Factor Are Synergistically Associated with the Liver Metastasis of Colorectal Cancer
- Renal Carcinogenicity of Concurrently Administered Fish Meal and Sodium Nitrite in F344 Rats
- Synergistic Effects of High-dose Soybean Intake with Iodine Deficiency, but Not Sulfadimethoxine or Phenobarbital, on Rat Thyroid Proliferation
- Lack of Effect of Soy Isoflavone On Thyroid Hyperplasia in Rats Receiving an Iodine-deficient Diet
- P-17 Sequential Observation of Acrolein-modified Protein and Effects of N-Acetylcysteins in Livers of Rats Treated with Carbon Tetrachloride.(Proceedings of the 27th Annual Meeting)
- P-14 Effects of antioxidants on spontaneous hepatic and renal lesions in LEC rats.(Proceedings of the 27th Annual Meeting)
- Lack of Modification by Environmental Estrogenic Compounds of Thyroid Carcinogenesis in Ovariectomized Rats Pretreated with N-bis(2-hydroxynronyl)nitrosamine (DHPN)
- Lack of Modifying Effects of Environmental Estrogenic Compounds on the Development of Thyroid Proliferative Lesions in Male Rats Pretreated with N-Bis(2-hydroxypropyl)nitrosamine(DHPN)
- Inhibitory Effects of 1'-Acetoxychavicol Acetate on N-Nitrosobis(2-oxopropyl)-amine-induced Initiation of Cholangiocarcinogenesis in Syrian Hamsters
- Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model
- Pathological assessment of the nervous and male reproductive systems of rat offspring exposed maternally to acrylamide during the gestation and lactation periods-a preliminary study
- P-39 Effect of t-buthylhydroquinone and sodium nitrite alone or in combination on the forestomach of rasH2 mice.(Proceedings of the 27th Annual Meeting)
- P-38 Carcinogenic susceptibility of phenolphthalein in heterozygous p53 deficient C57BL/6 and CBA mice.(Proceedings of the 27th Annual Meeting)
- 21B-04-1 Preliminary Repeated Dose (28 Days) Oral Toxicity Study of Flutamide to Establish the Efficacy of the "Enhanced OECD Test Guideline 407" in Rats.
- The Epstein-Barr Virus Early Antigen Inducing Indole Alkaloids, (-)-Indolactam V and Its Related Compounds, Produced by Actinomycetes
- Molecular profiling of genes showing altered expression in the livers of rats treated with non-genotoxic hepatocarcinogens for long-term (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Efficient Synthesis of Akolactone A via Pd-Catalyzed Carbonylation(Organic Chemistry)
- Inhibitory effects of aminoguanidine on thyroid follicular carcinoma development in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation
- Quantification of Cyanamide Contents in Herbaceous Plants
- Asymmetric syntheses of daedalin A and quercinol and their tyrosinase inhibitory activity
- Carcinogenic potential of alizarin and rubiadin, components of madder color, in a rat medium-term multi-organ bioassay
- Nerve Growth Factor-Inducing Activity of Hericium erinaceus in 1321N1 Human Astrocytoma Cells(Pharmacology)
- O-15 Gene expression profiling in the microdissected hypothalamic medial preoptic area of rat neonates exposed perinatally to ethinylestradiol : a dose-response study(ENDOCRINE SYSTEM/DEVELOPMENT AND REPRODUCTION/CARCINOGENICITY/TOXICOGENOMICS)(GENERAL SE
- Diguanidinobutane (Arcaine) Degradation in Rhodococcus sp. C-x
- Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus
- 1,2-Dehydrolactarolide A, a New Plant Growth Regulatory Lactarane Sesquiterpene from Lactarius vellereus
- Repraesentins D, E and F, New Plant Growth Promoters from Lactarius repraesentaneus
- Anti-inflammatory Cyathane Diterpenoids from Sarcodon scabrosus
- Myrsinoic Acid E, an Anti-inflammatory Compound from Myrsine seguinii(Organic Chemistry)
- New Plant Growth Promoters, Repraesentins A, B and C, from Lactarius repraesentaneus(Organic Chemistry)
- Daedalin A, a Metabolite of Daedalea dickinsii, Inhibits Melanin Synthesis in an in Vitro Human Skin Model
- A Tyrosinase Inhibitor, Daedalin A, from Mycelial Culture of Daedalea dickinsii
- Chalcone Tetramers, Lophirachalcone and Alatachalcone, from Lophira alata as Possible Anti-tumor Promoters
- A Major Decomposition Product, Citrinin H2, from Citrinin on Heating with Moisture(Food & Nutrition Science)
- Toxic effects of a horseradish extract and allyl isothiocyanate in the urinary bladder after 13-week administration in drinking water to F344 rats
- Lack of Modifying Effects of Cinnamaldehyde on Development of Lung Proliferative Lesions Induced by Urethane in Transgenic Mice Carrying the Human Prototype c-Ha-ras Gene