Chemopreventive Effects of Bovine Lactoferrin on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis
スポンサーリンク
概要
- 論文の詳細を見る
- 2000-06-30
著者
-
FUKUSHIMA Shoji
Department of Pathology, Osaka City University Medical School
-
WANIBUCHI Hideki
Department of Pathology, Osaka City University Medical School
-
TSUDA Hiroyuki
Experimental Pathology and Chemotherapy Division, National Cancer Center Research Institute
-
MASUDA Chikayoshi
Department of Urology, Osaka City University Medical School
-
Masuda Chikayoshi
Department Of Urology Osaka City University Medical School
-
Wanibuchi Hideki
Department Of Pathology Osaka City University Medical School
-
Wanibuchi Hideki
大阪府立成人病センター 分子生物学
-
Kishimoto Taketoshi
Department of Urology Osaka City University Medical School
-
Kim Taku
大阪市立大学 泌
-
OTANI Shuzo
Department of Second Biochemistry, Osaka City University Medical School
-
Tsuda Hiroyuki
Department Of Molecular Toxicology Nagoya City University Graduate School Of Medical Sciences
-
Tsuda H
Keio Univ. Yokohama‐shi Jpn
-
Tsuda Hiroyuki
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Kim Taku
Department Of Urology Osaka City University Medical School
-
SEKINE Kazunori
Experimental Pathology and Chemotherapy Division, National Cancer Center Research Institute
-
YANO Yoshihisa
Department of Biochemistry, Osaka City University Medical School
-
Yano Y
Department Of Biochemistry Osaka City University Medical School
-
Yano Yoshihisa
Department Of Biochemistry Osaka City University Graduate School Of Medicine
-
Wanibuchi H
Department Of Pathology Osaka City University Medical School
-
Otani S
Department Of Biochemistry Osaka City University Medical School
-
Otani Shuzo
Department Of Biochemistry Osaka City University Medical School
-
Otani Shuzo
Department Of Biochemistry Osaka City University Graduate School Of Medicine
-
Sekine Kazunori
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Fukushima Shoji
中央労働災害防止協会日本バイオアッセイ研究センター
-
Toriyama‐baba H
Experimental Pathology And Chemotherapy Division National Cancer Center Research Institute
-
Tsuda H
Department Of Obstrics And Gvnecology Toyama Medical And Pharmaceutical University
-
Kim Taku
Department Of Urology Osaka City University
-
Fukushima Shoji
Dept. Pathol. Osaka City University Medical School
-
Tsuda H
Division Of Oncological Pathology Aichi Cancer Center Research Institute
-
Fukushima Shoji
Department Of Pathology Osaka City University Medical School
-
Kishimoto Taketoshi
Department Of Pharmacology And Urology Osaka City University Medical School
-
Tashiro Koichiro
Department Of Urology Osaka City University Medical School
-
Fukuhara Kennichirou
Department Of Gastroenterological Surgery Osaka City University Graduate School Of Medicine
-
Fukushima Shoji
Department Of Gastroenterological Surgery Osaka City University Graduate School Of Medicine
-
Wanibuchi Hideki
Department Of Pathology Osaka City University Graduate School Of Medicine
-
YANO Yoshihisa
Department of Advanced Energy, Graduate School of Frontier Sciences, The University of Tokyo, 5-1-5 Kashiwanoha, Kashiwa, Chiba 277-8561, Japan
関連論文
- Lack of a Dose-response Relationship for Carcinogenicity in the Rat Liver with Low Doses of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline or N-Nitrosodiethylamine
- Continuous Exposure to Low-Dose Cisplatin and Apoptosis(Miscellaneous)
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Transdermal Drug Delivery by Electroporation Applied on the Stratum Corneum of Rat Using Stamp-Type Electrode and Frog-Type Electrode in Vitro
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- Use of Electroporation to Accelerate the Skin Permeability Enhancing Action of Oleic Acid
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Petroselinic Acid and Oleic Acid : Comparison of Enhanced Skin Permeability Relative to Affinity for Saturated Fatty Acids of Stratum Corneum
- Antitumor Effects of a Novel Lipophilic Platinum Complex (SM-11355) against a Slowly-Groing Rat Hepatic Tumor after Intra-Hepatic Arterial Administration
- Asclepic Acid(cis-ω7-Octadecenoic Acid) as a Skin Penetration Enhancer : Its Behavior and Effects on Rat Stratum Corneum and Dermis
- Enhancement of Propylene Glycol Distribution in the Skin by High Purity cis-Unsaturated Fatty Acids with Different Alkyl Chain Lengths Haiving Different Double Bond Position
- Skin Penetration Enhancing Action of cis-Unsaturated Fatty Acids with ω-9,and ω-12-Chain Lengths
- Enhancement of Propylene Glycol Permeation into Rat Dermis Using High-purity Oleic Acid and Subsequent Alteration of the Dermal Protein Structures
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Modulation of Dihydroxy-di-n-propylnitrosamine-induced Liver Lesion Development in Opisthorchis-infected Syrian Hamsters by Praziquantel Treatment in Association with Butylated Hydroxyanisole or Dehydroepiandrosterone Administration
- Relation between Intracellular Accumulation and Cytotoxic Activity of cis-[((1Rl,2R)-l,2-Cyclohexanediamine-N,N')bis(myristato)]platinuni(II) Suspended in Lipiodol
- Cytotoxicity of cis-[((1R,2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]-platinum (II) Suspended in Lipiodol in a Newly Established Cisplatin-resistant Rat Hepatoma Cell Line
- In Vitro Release of SM-11355,cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)]Platinum(II) Suspended in Lipiodol
- In Vitro Cytotoxicity of cis[((1R, 2R)-1,2-Cyclohexanediamine-N, N')bis(myristato)] platinum(II) Suspended in Lipiodol in Rat Hepatoma AH-109A Cells and Human Tumor Cell Lines
- Absence of β-catenin Mutations in Mouse Hepatoblastomas Induced by N,N-dimethylformamide
- Carcinogenic Potential of 2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) in Severe Combined Immunodeficient (SCID) Mice
- Lack of Inhibition of BBN-induced Bladder Carcinogenesis in C57BL/6 Mice by Intravesical Instillation of KRN 7000
- P6-02 Enhancement of thioacetamide-induced liver cirrhosis by estradiol 3-benzoate in the rats(LIVER AND DIGESTIVE SYSTEM/CIRCULATORY SYSTEM-1/DEVELOPMENT AND REPRODUCTION)(GENERAL SESSION BY POSTER PRESENTATION)(Proceedings of the 31st Annual Meeting)
- Carcinogenicity of Dimethylarsinic Acid in F344 Rats and p53 (+/-) Knockout and Wild Type C57BL/6J Mice. Relevance with Genetic Alterations and Oxidative DNA Damage (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual
- Establishment and characterization of a human colonic mucinous carcinoma cell line with predominant goblet-cell differentiation from liver metastasis
- -0860-CELLULAR COMPOSITION OF THE REPARATIVE TISSUE RESPONSE AT THE SITES OF PTCA : AN IMMUNOCYTOCHEMICAL ANALYSIS USING MONOCLONAL ANTIBODIES : THE 54th ANNUAL SCIENTIFIC MEETING OF THE JAPANESE CIRCULATION SOCIETY
- Existence of a no effect level for MeIQx hepatocarcinogenicity on a background of thioacetamide-induced liver damage in rats
- Differences in Sensitivity of F344 Rats from Different Breeders to Phenobarbital Hepatocarcinogenicity
- Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis
- Histological and Mucin Histochemical Study of Colon Ulcers Induced in Rats by a Rapid Freezing Method
- Chemopreventive Effect of Bovine Lactoferrin on 4-Nitroquinoline 1-Oxide-induced Tongue Carcinogenesis in Male F344 Rats
- Di-n-butyl Phthalate is Toxic to the Male Reproductive System and Its Toxicity is Enhanced by Thioacetamide Induced Liver Injury
- Food Restriction Inhibits the Growth of Intestinal Polyps in Multiple Intestinal Neoplasia Mouse
- Possible Involvement of Adaptation Mechanisms in the Achievement of an Ineffective Dose Range for the Carcinogenicity of Genotoxic Carcinogens
- Induction of DNA-adducts and increase of 8-hydroxy-2-deoxyguanosine, but no development of preneoplastic lesions in offspring liver with transplacental and trans-breast milk exposure to 2-amino-3, 8-dimethylimidazo [4, 5-f] quinoxaline (MeIQx) in rats
- Lack of Promoting Potential of Dimethylarsinic Acid in the Kidney of Male NCI-Black Reiter Rats
- p53 and H-ras Mutations and Microsatellite Instability in Renal Pelvic Carcinomas of NON/Shi Mice Treated with N-Butyl-N-(4-hydroxybutyl)-nitrosamine: Different Genetic Alteration from Urinary Bladder Carcinoma
- p53 in Multiple Human Urothelial Cancers: Assessment for Clonality by the Yeast p53 Functional Assay in Combination with p53 Immunohistochemistry
- Loss of Heterozygosity in (Lewis×F344)F_1 Rat Urinary Bladder Tumors Induced with N-Butyl-N-(4-hydroxybutyl) nitrosamine Followed by Dimethylarsinic Acid or Sodium L-Ascorbate
- Susceptibility of Four F_1 Hybrids of Male Rats to the Promoting Effects of Sodium L-ascorbate in Two-Stage Urinary Bladder Carcinogenesis
- Pharmacokinetics of Ephedrine and Pseudoephedrine after Oral Administration of Kakkonto to Healthy Male Volunteers
- Chemopreventive Effects of Bovine Lactoferrin on N-Butyl-N-(4-hydroxybutyl)nitrosamine-induced Rat Bladder Carcinogenesis
- Existence of a Threshold for the Genotoxic Carcinogens : Evidence from Mechanism-based Carcinogenicity Studies
- Ethanol Does Not Promote MeIQx-initiated Rat Colon Carcinogenesis Based on Evidence from Analysis of a Colon Cancer Surrogate Marker
- Upregulation of fibroblast growth factor receptor 3 and epidermal growth factor receptors, in association with Raf-1, in urothelial dysplasia and carcinoma in situ after the Chernobyl accident
- Hormesis in Carcinogenicity of Non-genotoxic Carcinogens
- Aberrant expression of E-cadherin and β-catenin in association with transforming growth factor-β1 in urinary bladder lesions in humans after the Chernobyl accident
- Dose-dependence of promotion of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline-induced rat hepatocarcinogenesis by ethanol : Evidence for a threshold
- Examination of the Rat Model of Liver Injury via Thioacetamide (TAA) or Carbon Tetrachloride (CCl_4)
- Significance of overexpression of metallothionein in mouse urinary bladder focal lesions induced by treatment with N-butyl-N-(4-hydroxybutyl)-nitrosamine
- Biphasic Increase of Epithelial DNA Synthesis in the Urinary Bladder of Rats Treated with a Tumor Promoter, Sodium L-ascorbate
- Transgenic Rats Carrying Human c-Ha-ras Proto-oncogene Are Highly Susceptible to N-Nitorosomethylbenzylamine Induction of Esphageal Tumorigenesis
- Ha-ras transgenic rats are highly Susceptible to mammary and esophageal carcinogenesis.
- Experimental Study of the Relationship between Perfluoro-Octyl Bromide Emulsion and Norepinephrine Release in Reperfusion Arrhythmia : Isolated Guinea Pig Heart Model
- Isoliquiritigenin, a flavonoid from licorice, reduces prostaglandin E_2 and nitric oxide, causes apoptosis, and suppresses aberrant crypt foci development
- Possible enhancing effects of atrazine and nonylphenol on 7, 12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats
- Preferential mammary carcinogenic effects of 2-amino-1-methyl-6-phenylimidazo[4, 5-b]pyridine (PhIP) in human c-Ha-ras proto-oncogene transgenic rats
- Down-regulation of 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx)-induceed CYP1A2 Expression Is Associated with Bovine Lactoferrin Inhibition of MeIQx-induced Liver and Colon Carcinogenesis in Rats
- Organotropic Chemopreventive Effects of n-3 Unsaturated Fatty Acids in a Rat Multi-organ Carcinogenesis Model
- A Ferulic Acid Derivative, Ethyl 3-(4'-Geranyloxy-3-methoxyphenyl)-2-propenoate, as a New Candidate Chemopreventive Agent for Colon Carcinogenesis in the Rat
- Establishment and characterization of three new rat renal cell carcinoma cell lines from N-ethyl-N-hydroxyethylnitrosamine-induced basophilic cell tumors
- Activation of Intestinal Mucosal Immunity in Tumor-bearing Mice by Lactoferrin
- Possible Chemopreventive Effects of Bovine Lactoferrin on Esophagus and Lung Carcinogenesis in the Rat
- Lack of effect of human c-Ha-ras proto-oncogene overexpression on prostate carcinogenesis in probasin/SV40 T antigen transgenic rats
- Mammary Carcinomas Induced in Human c-Ha-ras Proto-oncogene Transgenic Rats Are Estrogen-independent, but Responsive to d-Limonene Treatment
- Urinary bladder lesions induced by persistent chronic low-dose ionizing radiation
- Lack of Inhibitory Effects of an Anti-angiogenesis Drug, TNP-470, on Rat Urinary Bladder Papillomatosis Induced by Mechanical Stimulation
- Modulation of the Pharmacokinetics of 5'-Deoxy-5-fluorouridine and 5-Fluorouracil in Rats by Oral Co-administration of Acyclothymidine
- Anticancer Activity of Free γ-Linolenic Acid on AH-109A Rat Hepatoma Cells and the Effect of Serum Albumin on Anticancer Activity of γ-Linolenic Acid in Vitro
- Hydrolysis of 3', 5'-Dioctanoyl-5-fluoro-2'-deoxyuridine (FdUrd-C8) in Rabbit and Human Plasma and Its Release from Oily Solution
- Lactoferrin Inhibits Hepatitis C Virus Viremia in Patients with Chronic Hepatitis C: A Pilot Study
- Lack of Inhibitory Effects of Coumaperine from Pepper on the Promotion Stage of Chemical Hepatocarcinogenesis in the Rat
- Isolation of Differentiated Squamous and Undifferentiated Spindle Carcinoma Cell Lines with Differing Metastatic Potential from a 4-Nitroquinoline N-Oxide-induced Tongue Carcinoma in a F344 Rat
- Inhibitory effect of phenobarbital at low dose on rat hepatocarcinogenesis : the evidence for hormesis (CARCINOGENICITY) (GENERAL SESSION BY POSTER PRESENTATION) (Proceedings of the 30th Annual Meeting)
- Thresholds for Carcinogenicity of Environmental Carcinogens (SYMPOSIUM3: RECENT TOPICS ON THE RISK ASSESSMENT OF CHEMICAL CARCINOGENS) (Proceedings of the 30th Annual Meeting)
- Characteristic Upregulation of Glucose-Regulated Protein 78 in an Early Lesion Negative for Hitherto Established Cytochemical Markers in Rat Hepatocarcinogenesis
- Increased susceptibility to spontaneous lung cancer in mice lacking LIM-domain only 7
- Application of liquid chromatography-tandem mass spectrometry for the determination of opioidmimetics in the brain dialysates from rats treated with opioidmimetics intraperitoneally
- Lack of Enhanced Epithelial Cell Proliferation in the Urinary Bladder of Heterozygous p53 Knockout Mice Given Sodium Ortho-phenylphenate or Uracil
- Are tobacco use and urine pH indicated as risk factors for bladder carcinoma?
- Factors Influencing Library Penetration of Cancer Research-associated Journals in Japanese Universities and Research Institutions
- Classification of Renal Proliferative Lesions in Rats and/or Mice and Their Diagnostic Problems : Report from the Working Group of the Japanese Society of Toxicologic Pathology
- PREPARATION AND EVALUATION OF W/O TYPE AND W/O/W TYPE EMULSIONS CONTAINING AN ANTICANCER DRUG
- S4-5 Analysis of Arsenic Carcinogenicity : Using Animal Models(SYMPOSIUM 4: ARSENIC IN THE ENVIRONMENT AND THE TOXICITY)(Proceedings of the 31st Annual Meeting)
- Experimental Studies on Artificial Blood Usage for Hemodilution during Cardiopulmonary Bypass
- Evaluation of the Subchronic Toxicity of Dietary Administered Equisetum arvense in F344 Rats
- Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of P53 on Urinary Bladder Carcinogenesis
- Preparation of and Drug Release from W/O/W Type Double Emulsions Containing Anticancer Agents Using an Oily Lymphographic Agent as an Oil Phase(Pharmaceutical)