Inhibition by [Arg8]-Vasopressin of Long Term Potentiation in Guinea Pig Hippocampal Slice
スポンサーリンク
概要
- 論文の詳細を見る
We examined the effects of [Arg8]-vasopressin (AVP) on long term potentiation (LTP) of the field excitatory postsynaptic potentials at CA1 and CA3 synapses in adult guinea pig hippocampal slices. AVP (10 nM) depressed the magnitude of LTP without any effects on basal responses at both synaptic pathways. The depressive effect by AVP at CA1 synapses appears to be receptor-mediated since it was inhibited by an AVP V1-receptor antagonist, [Pmp1, Tyr(Me)2]-AVP. From these results, AVP may play an inhibitory role on the induction of LTP via V1 receptors in the guinea pig hippocampus.
- 社団法人 日本薬理学会の論文
- 1998-05-01
著者
-
Akaike A
Department Of Pharmacology Graduate School Of Pharmaceutical Sciences Kyoto University
-
Akaike Akinori
京都大学 薬学研究科生体機能解析学
-
Akaike A
Dep. Of Pharmacology Graduate School Of Pharmaceutical Sciences Kyoto Univ. Jpn
-
Akaike Akinori
京都薬科大学 病態生理
-
Akaike Akinori
Department Of Pharmacology Graduate School Of Pharmaceutical Sciences Kyoto University
-
Maeda T
Tottori Univ. Yonago Jpn
-
SATOH Masamichi
Department of molecular Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto university
-
Kaneko Shuji
Department Of Neuropharmacology Graduate School Of Pharmaceutical Sciences Kyoto University
-
Maeda Takehiko
Pharmacology Molecular Pharmacology Faculty Of Pharmaceutical Sciences Kyoto University
-
Satoh Masamichi
Department Of Molecular Pharmacology Faculty Of Pharmaceutical Science Kyoto University
-
SAKURAI Einosuke
Departments of Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto University
-
KANEKO Shuji
Neuropharmacology, Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto University
-
AKAIKE Akinori
Pharmacology, Molecular Pharmacology, Faculty of Pharmaceutical Sciences, Kyoto University
-
Sakurai Einosuke
Departments Of Molecular Pharmacology Faculty Of Pharmaceutical Sciences Kyoto University
-
Satoh Masamichi
Department Of Hygiene And Preventive Medicine Faculty Of Medicine Saitama Medical School
関連論文
- Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
- Mechanisms of Chronic Nicotine Treatment–Induced Enhancement of the Sensitivity of Cortical Neurons to the Neuroprotective Effect of Donepezil in Cortical Neurons
- Excitotoxicity-Associated p53 Expression in Adult Rat Retina Is Mediated by Calpain Activity but Not by Cl^- Influx
- Roles of Nicotinic Receptors in Acetylcholinesterase Inhibitor-Induced Neuroprotection and Nicotinic Receptor Up-Regulation(Functional Changes Induced by Long-Term Stimulation of Nicotinic Acetylcholine Receptors)
- Serofendic Acid Promotes Stellation Induced by cAMP and cGMP Analogs in Cultured Cortical Astrocytes
- Inhibition of glutamatergic transmission by morphine in the basolateral amygdaloid nucleus reduces pain-induced aversion
- PJ-104 Serofendic Acid, a Novel Substance Extracted from Fetal Calf Serum, Protects against Oxidative Stress in Neonatal Rat Cardiac Myocytes(Myocardial ischemia-reperfusion, basic/clinical-5 (IHD) PJ18,Poster Session (Japanese),The 70th Anniversary Annua
- Pharmacological Characteristics of Rotational Behavior in Hemiparkinsonian Rats Transplanted With Mouse Embryonic Stem Cell-Derived Neurons
- Serofendic acid protects from iodinated contrast medium and high glucose probably against superoxide production in LLC-PK1 cells
- Dual effect of serotonin on formalin-induced nociception in the rat spinal cord
- The Parkinsonian Models : Invertebrates to Mammals
- Effects of Nicotinic Receptor Agonists on Beta-Amyloid Beta-Sheet Formation
- Foreword(Functional Changes Induced by Long-Term Stimulation of Nicotinic Acetylcholine Receptors)
- Co-culture With the Striatum Attenuates N-Methyl-D-aspartate Cytotoxicity in Dopaminergic Neurons of Rat Mesencephalic Slice Cultures
- Bifemelane Protects Cultured Cortical Neurons Against N-Methyl-D-aspartate Receptor-Mediated Glutamate Cytotoxicity
- Protective Effect of MKC-231, a Novel High Affinity Choline Uptake Enhancer, on Glutamate Cytotoxicity in Cultured Cortical Neurons
- Suppressive effect of zinc ion on iNOS expression induced by interferon-γ or tumor necrosis factor-α in murine keratinocytes
- Involvement of apoptosis and cholinergic dysfunction in Alzheimer's disease
- EFFECTS OF OPIOID PEPTIDES ON NEURONAL ACTIVITIES OF THE CNS : STUDIES USING MICROELECTROPHORETIC METHOD
- Neuroprotective action of donepezil mediated by neuronal nicotinic receptors
- A Critical Role of TRPM2 in Neuronal Cell Death by Hydrogen Peroxide
- Donepezil Potentiates Nerve Growth Factor-Induced Neurite Outgrowth in PC12 Cells
- Contribution of endogenous glycine site NMDA agonists to excitotoxic retinal damage in vivo
- Mechanisms of oxygen glucose deprivation-induced glutamate release from cerebrocortical slice cultures
- Endogenous Factors Regulating Neuronal Death Induced by Radical Stress(Mitochondria and Neuroprotection)
- Retinal Neurotoxicity of Nitric Oxide Donors With Different Half-Life of Nitric Oxide Release: Involvement of N-Methyl-D-aspartate Receptor
- Ether Extract of Fetal Cakf Serum Protects Cultured Rat Cortical Neurons against Glutamate Cytotoxicity
- Effects of R-(-)-BPAP on the Expressions of Neurotrophins and Their Receptors in Mesencephalic Slices(Pharmacology)
- Na+/Ca2+ Exchanger Inhibitors Inhibit Neurite Outgrowth in PC12 Cells
- Effect of repeated cold stress on capsaicin-evoked release of glutamate from rat spinal dorsal horn slices
- POSSIBLE MECHANISM INVOLVED IN THE INHIBITORY ACTION OF U-50,488H, AN OPIOID κ AGONIST, ON GUINEA PIG HIPPOCAMPAL CA3 PYRAMIDAL NEURONS IN VITRO
- Involvement of Glutamate Receptors Within the Central Nucleus of the Amygdala in Naloxone-Precipitated Morphine Withdrawal- Induced Conditioned Place Aversion in Rats
- Apoptosis of cultured microglia by the deprivation of macrophage colony-stimulating factor
- Participation of cAMP and cAMP-dependent protein kinase in β-adrenoceptor-mediated interleukin-1β mRNA induction in cultured microglia
- Zn deficiency and hypertension
- Glutathione Biosynthesis via Activation of the Nuclear Factor E2–Related Factor 2 (Nrf2) – Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate
- Facilitative Effect of a Glutamate Transporter Inhibitor (2S,3S)-3-{3-[4-(Trifluoromethyl)benzoylamino]benzyloxy} aspartate on the Expression of Methamphetamine-Induced Behavioral Sensitization in Rats
- Enhanced production of monocyte chemoattractant protein-1 in the dorsal root ganglia in a rat model of neuropathic pain : possible involvement in the development of neuropathic pain
- Involvement of Locus Coeruleus Noradrenergic Neurons in Supraspinal Antinociception by α, β-Methylene-ATP in Rats
- Involvement of β_2-Adrenergic and μ-Opioid Receptors in Antinociception Produced by Intracerebroventricular Administration of α,β-Methylene-ATP
- Sensitization of the Adenylyl Cyclase System in Cloned κ-Opioid Receptor-Transfected Cells Following Sustained Agonist Treatment : A Chimeric Study Using G Protein α_/α_q Subunits
- Bremazocine Recognizes the Difference in Four Amino Acid Residues to Discriminate Between a Nociceptin/Orphanin FQ Receptor and Opioid Receptors
- Antinociceptive Effects of Oriental Medicine Kei-Kyoh-Zoh-Soh-Oh-Shin-Bu-toh in Mice and Rats
- Receptor-Mediated Modulation of Voltage-Dependent Ca^ Channels via Heterotrimeric G-proteins in Neurons
- Inhibitory Effects of Bifemelane on Brain Ca^ Channel Subtypes Expressed in Xenopus Oocytes
- Inhibition by [Arg8]-Vasopressin of Long Term Potentiation in Guinea Pig Hippocampal Slice
- Involvement of M_2 receptor in an enhancement of long-term potentiation by carbachol in Schaffer collateral-CA1 synapses of hippocampal slices
- Itch-associated response induced by intradermal serotonin through 5-HT_2 receptors in mice
- Different Effects of Intrathecal Neurotoxins fot serotonergic and Catecholaminergic Systems on Antinociceptive Actions of Kei-Kyo-Zoh-Soh-Oh-Shin-Bu-toh and Morphine in Rats
- Involvement of Spinal Substance P and Excitatory Amino Acids in Inflammatory Hyperalgesia in Rats
- Mechanisms of Chronic Nicotine Treatment-Induced Enhancement of the Sensitivity of Cortical Neurons to the Neuroprotective Effect of Donepezil in Cortical Neurons
- Roles of β- and α2-Adrenoceptors Within the Central Nucleus of the Amygdala in the Visceral Pain–Induced Aversion in Rats
- Endomorphin-1 Discriminates the μ-Opioid Receptor From the δ-and κ-Opioid Receptors by Recognizing the Difference in Multiple Regions
- Possible Involvement of Descending Serotonergic Systems in Antinociception by Centrally Administered Elcatonin in Mice
- YM-14673,a New Thyrotropin-Releasing Hormone Analog, Augments Long-Term Potentiation in the Mossy Fiber-CA3 System of Guinea Pig Hippocampal Slices
- Indeloxazine Augments Long-Term Potentiation in the Mossy Fiber-CA3 System of Guinea Pig Hippocampal Slices
- MECHANISM OF AN ELEVATION IN SYSTEMIC BLOOD PRESSURE INDUCED BY EXCESSIVE Zn INTAKE
- PATHOHISTOLOGICAL STUDY ON THE SKIN LESION OBSERVED IN ZINC DEFICIENT RATS
- EFFECTS OF Zn DEFICIENCY ON GENETIC HYPERTENSION
- APOPTOTIC CELL DEATH AND INDUCIBULE NITRIC OXIDE EXPRESSION IN TESTIS OF ZINC DEFICIENCY RATS
- ZINC AND APOPTOSIS : APOPTOTIC CELL DEATH IN TESTIS AND THYMUS OF ZINC DEFICIENCY MODELS
- ROLE OF ZINC IN BLOOD CIRCULATION : BLOOD PRESSURE AND RENAL BLOOD FLOW IN RATS WITH ZINC DEFICIENCY
- Morphological Changes of Erythrocytes and Reticulocytosis in Zinc-Deficient Rats
- Clay Mineralogy and Pedogenesis of Volcanic Ash Soils Influenced by Tropospheric Eolian Dust in Changbaishan, Sanjiaolongwan, and Wudalianchi, Northeast China
- Molecular biology of the opioid receptors: structures, functions and distributions
- BRADYKININ-INDUCED FLEXOR REFLEX OF RABBIT HINDLIMB FOR COMPARING ANALGESICS
- EFFECTS OF INDOMETHACIN AND THE OTHER ANTI-INFLAMMATORY AGENTS ON ACTIVATION OF DORSAL HORN CELL IN THE SPINAL CORD INDUCED BY INTRA-ARTERIAL INJECTION OF BRADYKININ
- Neuronal Nitric Oxide Synthase Is Crucial for Ganglion Cell Death in Rat Retinal Explant Cultures
- Na^+/Ca^ Exchanger Inhibitors Inhibit Neurite Outgrowth in PC12 Cells
- MECHANISMS OF THE ANTINOCICEPTIVE ACTION OF CARBAMAZEPINE AS REVEALED BY BRADYKININ-INDUCED TOOTHACHE METHOD
- INHIBITION OF THALAMIC AND HYPOTHALAMIC SOMATOSENSORY EVOKED POTENTIALS BY STIMULATION OF SUBSTANTIA NIGRA AND ITS MODIFICATION BY MORPHINE AND METHOTRIMEPRAZINE (LEVOMEPROMAZINE)
- Glutathione Biosynthesis via Activation of the Nuclear Factor E2-Related Factor 2 (Nrf2)-Antioxidant-Response Element (ARE) Pathway Is Essential for Neuroprotective Effects of Sulforaphane and 6-(Methylsulfinyl) Hexyl Isothiocyanate
- Roles of β- and α_2-Adrenoceptors Within the Central Nucleus of the Amygdala in the Visceral Pain-Induced Aversion in Rats
- ANALGESIC POTENCIES OF NON-NARCOTIC, NARCOTIC AND ANESTHETIC DRUGS AS DETERMINED BY THE BRADYKININ-INDUCED BITING-LIKE RESPONSES IN RATS
- SUPPRESSIVE EFFECT OF CIRAMADOL ON THE BRADYKINININDUCED ACTIVITIES OF THE LAMINA V-TYPE CELLS OF THE RAT SPINAL DORSAL HORN
- SITES OF ANALGESIC ACTION OF CIRAMADOL
- Glucocorticoids Decrease Astrocyte Numbers by Reducing Glucocorticoid Receptor Expression In Vitro and In Vivo
- FURTHER OBSERVATION ON THE ENHANCEMENT BY MORPHINE OF THE CENTRAL DESCENDING INHIBITORY INFLUENCE ON SPINAL SENSORY TRANSMISSION