Indeloxazine Augments Long-Term Potentiation in the Mossy Fiber-CA3 System of Guinea Pig Hippocampal Slices
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概要
- 論文の詳細を見る
The effects of indeloxazine and piracetam, which reportedly prevent experimental impairments of memory and learning, on long-term potentiation (LTP) of the population spike in the mossy fiber-CA3 system were studied in vitro using the guinea pig hippocampal slices. Indeloxazine (10^<-6> M) or piracetam (10^<-4> M) significantly augmented the LTP and the effect of indeloxazine on the LTP was approximately 100 times as potent as that of piracetam.
- 公益社団法人日本薬学会の論文
著者
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Ishihara Kumatoshi
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyoto University
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Satoh M
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyoto University
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Satoh Masamichi
Department Of Molecular Pharmacology Faculty Of Pharmaceutical Science Kyoto University
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Katsuki H
Univ. Tokyo Tokyo Jpn
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Katsuki Hiroshi
Department Of Chemical Pharmacology Faculty Of Pharmaceutical Sciences The University Of Tokyo
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Sugimura Masunobu
Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kyoto University
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Satoh Masamichi
Department Of Hygiene And Preventive Medicine Faculty Of Medicine Saitama Medical School
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Ishihara Kumatoshi
Department of Neurology and Neurosurgery, The Montreal Neurological Institute and Hospital
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