Synthesis of cytidine, uridine, and adenosine 5'-(2,6-diamino-2,6-dideoxy-.ALPHA.-D-glucopyranosyl diphosphates) (neosamine C-CDP, -UDP, and -ADP).
スポンサーリンク
概要
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Three potential biosynthetic intermediates for aminocyclitol antibiotics, neosamine C-CDP, -UDP, and -ADP, have been synthesized from D-glucosamine by chemical means. 2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl phosphate, derived from the corresponding glycosyl bromide, was condensed with three nucleosides (CMP, UMP and AMP) by a known procedure. The configurations of the neosamine C nucleoside diphosphates have been confirmed by <SUP>13</SUP>C NMR spectra.
- 公益社団法人 日本化学会の論文
著者
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Tadano Kin-ichi
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Suami Tetsuo
Department of Applied Chemistry Faculty of Engineering Keio University
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Tsuchiya Tohru
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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Rinehart Kenneth
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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