Synthetic studies on the validamycins. III. Bromination of DL-tri-O-acetyl-(1,3/2)-4-methylene-5-cyclohexene-1,2,3-triol. Preparation of several branched-chain unsaturated cyclitols related to valienamine.
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概要
- 論文の詳細を見る
Bromination of DL-tri-<I>O</I>-acetyl-(1,3/2)-4-methylene-5-cyclohexene-1,2,3-triol with bromine in an appropriate solvent yielded mainly two 1,4-addition products, from which several branched-chain unsaturated cyclitols, related to biologically interesting valienamine, were selectively prepared. Reaction courses are discussed for the bromination of the diene and the debromination of the bromo(bromomethyl)cyclohexenetriol triacetates obtained under various conditions.
- 公益社団法人 日本化学会の論文
著者
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Ogawa Seiichiro
Department Of Applied Cemistry Faculty Of Science And Technology Keio University
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Suami Tetsuo
Department of Applied Chemistry Faculty of Engineering Keio University
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Abe Yasuo
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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Toyokuni Tatsushi
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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