A New, Convenient Cell-Based Screening Method for Small-Molecule Glycolytic Inhibitors
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概要
- 論文の詳細を見る
To counteract active glycolysis in tumors, we developed a new, convenient cell-based screening system to identify an inhibitor of glycolysis. Using this system, we searched for an inhibitor in the synthetic Carbasugar library and found two candidates. It was found that both inhibited glycolysis by suppressing the glucose uptake step in tumor cells.
- 社団法人 日本農芸化学会の論文
- 2011-02-23
著者
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IMOTO Masaya
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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Tashiro Etsu
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Imoto Masaya
Department Of Agricultural Chemistry Faculty Of Agriculture Yamaguchi University
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Imoto Masaya
Department Of Biosciences And Informatics Faculty Of Science And Technology Keio University
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KITAGAWA Mitsuhiro
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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Ogawa Seiichiro
Department Of Applied Cemistry Faculty Of Science And Technology Keio University
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Kitagawa Mitsuhiro
Department Of Biosciences And Informatics Faculty Of Science And Technology Keio University
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MISAWA Mayuko
Department of Biosciences and Informatics, Faculty of Science and Technology, Keio University
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Misawa Mayuko
Department Of Biosciences And Informatics Faculty Of Science And Technology Keio University
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Imoto Masaya
Chemical Biology Laboratory Department Of Biosciences And Informatics Faculty Of Science And Technology Keio University
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