Inhibition of T Cell Receptor-mediated Signal Transduction by Erbstatin
スポンサーリンク
概要
- 論文の詳細を見る
Erbstatin, a tyrosine kinase inhibitor, inhibited p59^<fyn>- and p56^<1ck>-kinases in vitro with IC_<50>s of 0.21 and 0.18μg/ml, respectively. Inositol phosphates formation, enhanced by anti-CD3, wasalso inhibited by erbstatin. Moreover, erbstatin treatment prevented anti-CD3-induced interleukin 2 (IL-2) production, but phorbol ester-induced IL-2 production was not affected by erbstatin.
- 社団法人日本農芸化学会の論文
- 1994-09-23
著者
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Nakamura Takeshi
Department of Cardiovascular Medicine, Kyoto Prefectural University of Medicine
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UMEZAWA Kazuo
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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TANAKA Shin-ichiro
Department of Internal Medicine, Hidaka Hospital
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IMOTO Masaya
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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Imoto Masaya
Department Of Agricultural Chemistry Faculty Of Agriculture Yamaguchi University
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Imoto Masaya
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Tanaka Shin-ichiro
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Tanaka Shin-ichiro
Department Of Applied Chemistry Faculty Of Science And Technology
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Umezawa Kazuo
Department Of Applied Chemistry Faculty Of Science And Technology
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Nakamura Takeshi
Department Of Agricultural Chemistry Faculty Of Agriculture Kyoto University
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