Synthetic studies on the validamycins. IX. Synthesis of some racemic isomers of validoxylamine A.
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概要
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Two racemic isomers of validoxylamine A have been synthesized by use of coupling reactions of the protected DL-validamine and the allylbromides, the precursors of the unsaturated branched-chain cyclitol moiety. The racemic diastereomers thus formed can be separated by chromatography on silica gel. It indicates that optically pure validoxylamine A analogs should be obtained if chiral validamine derivative is used in place of the racemate.
- 公益社団法人 日本化学会の論文
著者
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Ogawa Seiichiro
Department Of Applied Cemistry Faculty Of Science And Technology Keio University
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Suami Tetsuo
Department of Applied Chemistry Faculty of Engineering Keio University
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Toyokuni Tatsushi
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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