Synthetic studies on the validamycins. I. Synthesis of .BETA.-D-glucopyranosylvalidamine: 1L-2-O-(.BETA.-D-Glucopyranosyl)-(1,3,4/2,6)-4-amino-6-hydroxymethyl-1,2,3-cyclohexanetriol.
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概要
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β-D-Glucopyranosylvalidamine, the structure of which had first been assigned to a degradation product of validamycin A, was synthesized by condensation of a protected validamine with 2,3,4,6-tetra-<I>O</I>-acetyl-α-D-glucopyranosyl bromide, followed by removal of protecting groups. The synthesized β-D-glucopyranoside was not identical with an authentic sample derived from the antibiotic.
- 公益社団法人 日本化学会の論文
著者
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Chida Noritaka
Department Of Applied Chemistry Faculty Of Science And Technology Keio University
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Ogawa Seiichiro
Department Of Applied Cemistry Faculty Of Science And Technology Keio University
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Suami Tetsuo
Department of Applied Chemistry Faculty of Engineering Keio University
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Shibata Yasuhito
Department of Applied Chemistry, Faculty of Science and Technology, Keio University
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