咽喉頭,口腔領域の炎症性疾患に対するアズノ-ルS錠(AZ-S)の臨床的研究

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The Azunol-S tablet (AZ-S: water-soluble Azunol 5mg), to be inserted into the labiogingival region of the upper jaw, was administered to patients having pharyngolaryngeal and oral inflammations or having undergone tonsillectomy at doses of 1-2 tablets, 3-4 times daily for 7 days.1) The total number of patients was 96; pharyngitis 55, pharyngo-laryngitis 24, tonsillitis 11, post-tonsillectomy 4 and stomatitis 2 cases.The rate of global effectiveness was 61.5% (excellent and good response) and 88.5% (the above two and moderate response).2) The rate of global effectiveness in pharyngitis was 61.8% (excellent and good) and 92.7% (the above two and moderate), and that in pharyngo-laryngitis was 50% and 83.3% respectively.3) Spontaneous pain, swallow pain, strange feeling, redness and swelling were greatly relieved in acute cases of pharyngitis and pharyngo-laryngitis, and spontaneous pain, swallow pain, strange feeling and swelling were alleviated in chronic cases.4) As to patients' feeling for the administration method of tablets, most of them answered "good" or "not nervous about it though aware of it".5) Slight side effects such as gastric disturbance were observed in 3 of the 96 cases. Other systemic or local side effects were not complained of, however.The AZ-S tablet is regarded as safe and effective in pharyngo-laryngeal and oral inflammations.
耳鼻咽喉科臨床学会の論文