滲出性中耳炎に対するアゼプチンの有用性

概要

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The usefulness of the anti allergic agent Azeptin® was evaluated in 182 patients with otitis media with effusion. Azeptin® was administered in a dose of 2 mg twice daily for 4 to 8 weeks patients over 6 years of age and in a dose of 1mg to those under 5 years of age.The efficacy of Azeptin® was determined by evaluating the response to treatment of subjective symptoms such as tinnitus, hearing impairment, and feeling of ear, blockage tympanic findings and hearing acuity.The final general improvement rate was 39.5% for good to excellent responses and 65.0% for fair to excellent responses.Notably improved were hearing impairment, feeling of ear blockage and appearance the tympanic membrane and reduced fluid retention.Side effects were experienced by 2.2% of the patients: drowsiness, gastric discomfort, vomiting and a bitter aftertaste (1 case each).