純音刺激と聴器病変,特にCortis organの病変の拡がりかたについて

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This paper reports influence of pure tone stimulation on histopathological changes of Cortis organ of normal guinea pig. The sound stimulations were conducted through metal tube directly from 1000, 2000 and 4000cps pure tone souce to ear drum of guinea pig, and the sound level just before the ear drum was settled between 100 and 135db. The results obtained were as follows:1. On the 1000cps stimulation group, critical intensity line was determined, which was connected with the intensity and duration of sound stimulation and was able to separate the reversible and irreversible change of Cortis organ, 2. On the 1000cps stimulation group, the begining of the most demaged region was observed between 10.0 and 10.6mm from basal end.3. On the 1000cps stimulation group, when the sound level was intensified, the demaged region was extended little to helicotrema but chiefly to basal end and the center of the demaged region was observed between 8.0 and 9.4mm from basal end.4. On the 2000cps stimulation group, the center of demaged region was observed between 7.0 and 7.8mm from basal end and was near to basal end compared with that was on the 1000cps stimulation group.5. On the 4000cps stimulation group, the center of demaged region was near to basal end compared with that was on 2000cps stimulation group, and observed between 6.4 and 7.2mm from basal end.
社団法人日本耳鼻咽喉科学会の論文