Strain Gauge Force Transducer and Its Application in a Pig Model to Evaluate the Effect of Probiotic on Colonic Motility

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概要

• 論文の詳細を見る

• The aim of this study was to investigate the effect of probiotic, i.e., fermented milk prepared with Lactobacillus casei strain Shirota, on colonic motility by the strain gauge force transducer (SGFT) in a pig model. The contractions of the circular muscle layer of the cecum, upper colon, lower colon, and terminal colon in pigs were directly measured in conscious status by this method. This method was useful for quantitatively evaluating the effects of stimuli on colonic motility. Feeding significantly stimulated the motilities of the upper and lower colon. Defecation significantly stimulated the motilities of the upper and terminal colon. Two weeks feeding of the fermented milk significantly activated the response to feeding in four portions of the large intestine. It increased motility of the terminal colon that did not promote defecation. The frequency of defecation from 9:00 to 10:00 (the period just after the morning meal) increased significantly, but from 0:00 to 1:00 (the midnight period) it decreased as a result of the ingestion of fermented milk. Such effects of the fermented milk on motility of the terminal colon are discussed in relation to the movement of digesta. The effects may relate to the stimulation of colonic fermentation as shown by a decrease in fecal pH.

• 財団法人 学会誌刊行センターの論文
• 2001-10-01

著者

• Ushida Kazunari

  Laboratory Of Animal Science Kyoto Prefectural University

• Ushida K

  Laboratory Of Animal Science Kyoto Prefectural University

• Ushida Kazunari

  京都府立大学 農学部動物生産学講座

• Ohashi Yuji

  Laboratory Of Animal Science Kyoto Prefectural University:(present Address)laboratory Of Food Hygien

• Inoue Ryo

  京都府立大学 動物機能学

• Inoue Ryo

  Laboratory of Animal Science, Kyoto Prefectural University

• Tanaka Ken-Ichi

  Laboratory of Molecular Microbiology, School of Agriculture, Nagoya University

• UMESAKI Yoshinori

  Yakult Central Institute for Microbiological Research

• Inoue R

  Tohoku Univ. Miyagi‐ken Jpn

• Inoue Ryo

  Laboratory Of Animal Science Kyoto Prefectural University

• Tanaka K

  Laboratory Of Animal Science Kyoto Prefectural University

• Tazuya Keiko

  Faculty Of Pharmaceutical Sciences Mukogawa Women's University

• Ushida Kazunari

  Kyoto Prefectural Univ. Kyoto Jpn

• Ohashi Yuji

  Laboratory Of Animal Science Kyoto Prefectural University

• Tanaka Ken-ichi

  Laboratory Of Microbiology School Of Agriculture Nagoya University

• TANAKA Ken-ichi

  Laboratory of Animal Science, Kyoto Prefectural University

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