97 マメ科薬用植物サポニンの研究

概要

論文の詳細を見る
Gleditsia saponin C (1), and Entada saponin-II (4), -III (5) and -IV (6) were isolated and investigated to prove as being bisdesmosidic saponins containing oleanane type triterpene as a sapogenin and eight sugar units,respectively, and these saponins are those having highest molecular size so far isolated. Although a triterpenoid glycoside containing an amino sugar has been isolated, 4, 5 and 6 are the first examples containing N-acetyl-glucosamine as a sugar components of high molecular saponins. Further, 1, 4, 5 and 6 are the first examples of the saponins containing monoterpene moiety in their molecules. Since earlier workers noted an in vitro antitumor activity in the saponin of Entada, this has been tested using 4, 5 and 6 on L-5178Y tumor cells to give some positive results.
天然有機化合物討論会の論文
1985-09-07