SYNTHESIS OF SAFRAMYCINS. I. TOTAL SYNTHESIS OF (±)-SAFRAMYCIN B AND ITS CONGENERS.(Communication to the Editor)
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概要
- 論文の詳細を見る
We describe the total synthesis of the dimeric isoquinolinequinone antibiotic saframycin B (1) from tricyclic lactam 3. The key step is the stereoselective intramolecular cyclization of the aminoacetal 6. The structure of the pentacyclic intermediate 8 was confirmed by X-ray crystallography.
- 社団法人日本薬学会の論文
- 1987-05-25
著者
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坂井 進一郎
千葉大院薬
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坂井 進一郎
Faculty of Pharmaceutical Sciences, Chiba University
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久保 陽徳
Meiji College of Pharmacy
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山内 玲子
Meiji College of Pharmacy
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斎藤 直樹
Meiji College of Pharmacy
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坂井 進一郎
Faculty Of Pharmaceutical Sciences Chiba University
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