Imidazo[2,1-b]benzothiazoles. I
スポンサーリンク
概要
- 論文の詳細を見る
A series of [2-[p-(un)substituted phenyl]imidazo[2,1-b]benzothiazo-3-yl]acetic acid derivatives was prepared. The 2-[p-(un)substituted phenyl]imidazo[2,1-b]benzothiazoles (2a-e) were first converted to the corresponding 3-(dimethylaminomethyl) Mannich bases (3a-e), which in turn were converted to the methiodide salts (4a-d) and thence to the desired products (7a-e), (see Chart 1).Some of the acetic acid derivatives (7a, c, d) were tested for analgesic and antiinflammatory activities by means of carrageenin-induced paw edema, streching by acetic acid and capillary permeability inhibition assays.
- 公益社団法人日本薬学会の論文
- 1988-12-25
著者
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坂井 進一郎
Faculty of Pharmaceutical Sciences, Chiba University
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坂井 進一郎
Showa College of Pharmaceutical Sciences
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EL-GENDY Mahmound
Department of Pharmaceutical Medical Chemistry, Faculty of Pharmacy, Assiut University
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EL-GENDY Mahmoud
Faculty of Pharmacy, Assiut University
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El-gendy Mahmound
Department Of Pharmaceutical Medical Chemistry Faculty Of Pharmacy Assiut University
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El-shorbagi Abdel-nasser
Faculty Of Pharmaceutical Sciences Chiba University
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坂井 進一郎
Faculty Of Pharmaceutical Sciences Chiba University
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OMAR Nabil
Faculty of Pharmacy, Assiut University
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FARAG Hassan
Faculty of Pharmacy, Assiut University
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Omar Nabil
Faculty Of Pharmacy Assiut University
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Farag Hassan
Faculty Of Pharmacy Assiut University
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