STRUCTURE OF THEONELLAPEPTOLIDE IE, A NEW TRIDECAPEPTIDE LACTONE FROM AN OKINAWAN MARINE SPONGE, THEONELLA SP. (THEONELLIDAE)(Communication to the Editor)

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概要

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• A new tridecapeptide lactone named theonellapeptolide le (2), isolated from an Okinawan marine sponge of Theonella sp. (Theonellidae) together with theonellapeptolide Id (1) and some other minor peptide lactones, has been determined on the basis of chemical and physicochemical evidence. A new HPLC analysis method for N-methyl amino acids has been developed to analyze the amino acid composition of theonellapeptolide Id (1) and le (2). Ie (2) contains one N-methyl-3-alanine and two 3-alanine moieties among thirteen constituent amino acids whereas Id (1) contains three β-alanine moieties.

• 公益社団法人日本薬学会の論文
• 1987-05-25

著者

• 北川 勲

  Faculty of Pharmaceutical Sciences, Osaka University

• 小林 資正

  Faculty of Pharmaceutical Sciences, Osaka University

• 李 南庚

  Faculty of Pharmaceutical Sciences, Osaka University

• 渋谷 博孝

  Faculty of Pharmaceutical Sciences, Osaka University

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 李 南庚

  Faculty Of Pharmaceutical Sciences Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

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