Syntheses of 2-Acetamido-2-deoxy-4-O-β-D-galactopyranosyl-D-glucopyranose (N-Acetyllactosamine) Derivatives
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概要
- 論文の詳細を見る
In order to provide useful key intermediates for syntheses of complex oligosaccharides, anomeric 1,2', 3', 4', 6,6'-hexa-O-acetyl-N-acetyllactosamines (8 : α, and 9 : β) and the corresponding 3-O-benzyl ethers (5 : α, and 6 : β) were synthesized. Condensation of 1,6-anhydro-3-O-benzyl-β-N-acetylglucosamine with acetobromogalactose by a conventional Koenigs-Knorr procedure, followed by selective acetolysis of the 1,6-anhydro-β-linkage, provided 5 and 6. Debenzylation of 5 and 6 gave 8 and 9,respectively.
- 公益社団法人日本薬学会の論文
- 1983-02-25
著者
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手島 節三
名古屋市立大学薬学部
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手島 節三
Faculty of Pharmaceutical Sciences, Nagoya City University
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手島 節三
Faculty Of Pharmaceutical Sciences Nagoya City University
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伊藤 嘉雄
Faculty Of Pharmaceutical Sciences Nagoya City University
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