Selective Benzoylation of 1,6-Anhydro-4', 6'-O-benzylidene-β-maltose
スポンサーリンク
概要
- 論文の詳細を見る
Selective benzoylation of 1,6-anhydro-4', 6'-O-benzylidene-β-maltose (1), using 2 molar equivalents of benzoyl chloride in pyridine at ca. -10°, yielded five benzoates which were designated 2 to 6 in order of decreasing Rf value on TLC. After column chromatography on silica gel, compounds 2 to 6 were separated as the 2,2', 3,3'-tetrabenzoate (2,1.2%), 2,2', 3'-tribenzoate (3,2.8%), 2,2'-dibenzoate (4,9%), 2', 3'-dibenzoate (5,7.3%), and 2'-benzoate (6,48%), respectively. Thus, the order of reactivities of the secondary hydroxyl groups in 1 is 2'>2,3'>3. Compound 3 to 6 have potential value in the chemical modification of maltose or the synthesis of maltose-containing oligosaccharides.
- 社団法人日本薬学会の論文
- 1976-06-25
著者
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森 雅美
金城学院大学薬学部
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森 雅美
名古屋市立大学看護学部(生化学)
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森 雅美
愛知きわみ看護短期大学
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手島 節三
Faculty of Pharmaceutical Sciences, Nagoya City University
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羽賀 正信
Faculty of Pharmaceutical Sciences, School of Medicine, Hokkaido University, Nishi-5-chome, Kita-12-
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手島 節三
Faculty Of Pharmaceutical Sciences Nagoya City University
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羽賀 正信
Faculty Of Pharmaceutical Sciences Nagoya City University
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森 雅美
Faculty of Pharmaceutical Sciences, Nagoya City University
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羽賀 正信
Faculty Of Pharmaceutical Sciences Health Sciences University Of Hokkaido
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