アスパラギン結合型糖蛋白質糖鎖の部分合成
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概要
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This article describes synthetic methods for constituent mono-and oligo-saccharides existing in asparagine-linked glycan of glycoprotein. The target compounds are L-fucose, <I>N</I>-acetyllactosamine, di-<I>N</I>-acetylchitobiose, core pentasaccharide, and, di-and tri-mannopyranosyl-<I>N</I>-acetylglucosamines. Scope and limitation of chemical syntheses of oligosaccharides are generally discussed. Most of this article is based on the papers reported from this laboratory since 1979.
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