錠剤内の粒子配列について(第3報)圧縮過程でのアスピリン結晶粒子の配列の変化
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概要
- 論文の詳細を見る
The degree of preferred orientation of aspirin crystals in a tablet as a function of compression force was measured using the X-ray diffraction method. Preferred orientation took place during compression and the degree was affected by the size and morphology of the crystals. Thin, plate-like crystals had the strong tendency to orient preferentially at an early stage of compression, while pulverized crystals oriented gradually at over 100 kg/cm^2 of the compression force. In addition, volume, specfic surface area, pore size distribution and breaking strength of the tablets were measured and the relationship among these factors was investigated.
- 公益社団法人日本薬学会の論文
- 1979-09-25
著者
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仲井 由宣
千葉大学薬学部
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福岡 英平
東邦大学薬学部
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仲井 由宣
千葉大学
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福岡 英平
School of Pharmaceutical Sciences, Toho University
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中川 寛
鐘紡(株)・薬品研究所
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福岡 英平
School Of Pharmaceutical Sciences Toho University
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福岡 英平
Faculty Of Pharmaceutical Sciences Chiba University:(present Address)faculty Of Pharmaceutical Scien
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中川 寛
Pharmaceuticals Research Center Kanebo Ltd.
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中川 寛
鐘紡(株)薬品研究所
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中川 寛
鐘紡
関連論文
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- オクテット
- オクテット
- 製剤中の医薬品の分子状態について
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