Isocarbostyril関連化合物の合成研究(第5報)2-Acylamido-3-aminoisocarbostyrilの閉環反応
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概要
- 論文の詳細を見る
Heating of 2-acylamido-3-aminosocarbostyrils, having an acidic hydrogen at 2-acylamido group, in acetic acid gave the corresponding 1-H (or 3-H), 5H-s-triazolo [1,5-b]-isoquinolin-5-one derivatives, but, in the absence of acidic hydrogen, the cyc1ization occurred in alkaline medium at a room temperature. It was also found that the thermal decomposition of 4,5- or 2,5-disubstituted 3-(o-carboxybenzoyl)-s-triazole derivatives to phthalic anhydride and the substituted s-triazo1e took place easily.
- 公益社団法人日本薬学会の論文
- 1974-01-25
著者
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太田 俊作
京都薬科大学
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岡本 正夫
Kyoto Pharmaceutical University
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太田 俊作
京都薬科大学薬学部
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岡本 正夫
京都薬科大学
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木本 正七郎
京都薬科大学
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川端 哲郎
京都薬科大学
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川端 哲郎
Analytical Research Laboratories of Fujisawa Pharmaceutical Co., Ltd.,
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川端 哲郎
Analytical Research Laboratories Of Fujisawa Pharmaceutical Co. Ltd.
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