One-Step Synthesis of 1,2,3,4-Tetrahydrobenzo[g]quinazoline-5,10-dione Derivatives from Vitamin K_3

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概要

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• The reactions of 2-halogenonaphthoquinones (5,13,14 and 15) and 2-methyl-1,4-naphthoquinone (20; vitamin K_3) with primary and secondary amines were examined. 1,3-Dialkyl-1,2,3,4-tetrahydrobenzo[g]quinazoline-5,10-diones (9) were obtained in moderate yields by treating 20 with formaldehyde in primary amines. A plausible reaction path-way is also presented.

• 社団法人日本薬学会の論文
• 1994-09-15

著者

• 神田 陽子

  Kyoto Pharmaceutical University

• 太田 俊作

  Kyoto Pharmaceutical University

• 日向 靖成

  Kyoto Pharmaceutical University

• 山下 正行

  Kyoto Pharmaceutical University

• 川崎 郁勇

  Kyoto Pharmaceutical University

• 堀江 忍

  Kyoto Pharmaceutical University

• 川崎 郁勇

  京都薬大

• 太田 俊作

  京都薬科大学薬学部

• 川崎 郁勇

  Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University:school Of Pharmaceutica

• 太田 俊作

  Kyoto College Of Pharmacy

• 山下 正行

  京都薬科大学薬学部

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