Total Synthesis of Kealiiquinone, an Imidazole Marine Alkaloid
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概要
- 論文の詳細を見る
The total synthesis of kealiiquinone (1), a highly substituted imidazole marine alkaloid isolated from sponge, was achieved via nine reaction steps starting from 1-methyl-1H-imidazole (5). The synthesis is based on the selective introduction of appropriate carbogenic substituents and protecting groups into the imidazole ring followed by an intramolecular cyclization of the substituents on the C4- and the C5-positions. The structure of the synthesized kealiiquinone was confirmed by X-ray crystallographic analysis.
- 公益社団法人日本薬学会の論文
- 1997-09-15
著者
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OHTA Shunsaku
Kyoto Pharmaceutical University
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KAWASAKI Ikuo
Kyoto Pharmaceutical University
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YAMASHITA Masayuki
Kyoto Pharmaceutical University
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川崎 郁勇
Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University:school Of Pharmaceutica
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Ohta S
Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University
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TAGUCHI Norio
Kyoto Pharmaceutical University
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Taguchi N
Kyoto Pharmaceutical Univ. Kyoto Jpn
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Yamashita Masayuki
Kyoto Pharmaceutical Univ. Kyoto Jpn
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Kawasaki Ikuo
Kyoto Pharmaceutical Univ.
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Yamashita Masayuki
Department of Functional Molecular Chemistry, Kyoto Pharmaceutical University
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