Preparation and Characteristics of Antibacterial Sepiolite Containing Povidone-Iodine as a Useful Pharmaceutical Product for Patient Care
スポンサーリンク
概要
- 論文の詳細を見る
Providone-iodine (PVP-I), an antibacterial medicine, was infiltrated in sepiolite (SPL). The available iodine content in this new pharmaceutical product, a sepiolite preparation containing povidone-iodine (PVP-I-SPL), was retained at 98.9 and 98.3% during storage at 40℃ for 3 and 6 months, respectively. The effective removal of various gasses, including ammonia, hydrogen sulfide, ethylmercaptan and acetaldehyde, was achieved by use of PVP-I-SPL. Especially, the concentration of ammonia gas was reduced more tha half after 30 min of exposure, suggesting that PVP-I-SPL has excellent ability to adsorb ammonia gas. The satisfactory antibacterial effect of PVP-I-SPL was also obtained by testing its minimum bactericidal concentration (MBC). No irritation reactions to the rabbit auricle or ophthalmic mucosa or to human skin were observed by the skin irritation test.The PVP-I-SPL preparation has bactericidal activity and gas-adsorbing ability; therefore, this pharmaceutical product should be useful for the prevention of infections and deodorization in hospital rooms and houses, as well as in nursing homes for elderly people.
- 公益社団法人日本薬学会の論文
- 1999-01-15
著者
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KATSUYAMA Yoshihiko
Department of Pharmacy, Shinshu University Hospital
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Ogata Hiroyuki
Department Of Transfusion Service Shinshu University Hospital
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INOUE Hiroaki
Department of Physics, Sophia University
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OHTA SHIN
Department of Pharmacy, Shinshu University Hospital
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NAGAI KATSUHIRO
Department of Pharmacy, Shinshu University Hospital
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ZENDA HIROSHI
Department of Pharmacy, Shinshu University Hospital
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MARUYAMA Masataka
Department of Pharmacy, Shinshu University Hospital
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ATOBE Osamu
Department of Pharmacy, Shinshu University Hospital
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YAMATO Susumu
Department of Analytical Chemistry, Niigata College of Pharmacy
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TACHIKAWA Eiichi
Department of Pharmacology, School of Medicine, Iwate Medical University
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Katsuyama Yoshihiko
Department Of Pharmacy Shinshu University School Of Medicine
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Katsuyama Yoshihiko
Department Of Hospital Pharmacy Shinshu University School Of Medicine
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Atobe Osamu
Department Of Pharmacy Shinshu University School Of Medicine
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Ohta S
Department Of Functional Molecular Chemistry Kyoto Pharmaceutical University
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Ohta Shin
Pharmaceutical Health Care And Sciences Tokyo Univ. Of Pharmacy And Life Sci.
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Ohta Shin
Department Of Hospital Pharmacy Shinshu University School Of Medicine
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Zenda Hiroshi
Department Of Pharmacokinetics Hoshi University
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大和 進
Pharmaceutical And Analytical Chemistry Niigata Univ. Of Pharmacy And Applied Life Sciences
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Ogata H
Department Of Transfusion Service Shinshu University Hospital
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Tachikawa E
Department Of Pharmacology School Of Medicine Iwate Medical University
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Tachikawa Eiichi
Department Of Pharmacology Faculty Of Pharmacy Iwate Medical University
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Inoue Hiroaki
Department Of Animal Science Obihiro University Of Agriculture And Veterinary Medicine
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Nakayama K
Department Of Pharmacy Shinshu University Hospital
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Maruyama Masataka
Dep. Of Pharmacy Shinshu Univ. Hospital
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Maruyama Masataka
Department Of Gastroenterology St. Luke's International Hospital
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Inoue Hiroaki
Department Of Pharmacy Shinshu University Hospital
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Maruyama Masataka
Department Of Gastroenterology St Luke's International Hospital
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Tachikawa Eiichi
Department Of Endocrine Pharmacology Tokyo University Of Pharmacy And Life Sciences
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Ogata Hiroyuki
Department of Psychiatry, Dokkyo Medical University Koshigaya Hospital
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Katsuyama Yoshihiko
Department of Hospital Pharmacy
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Yamato Susumu
Department of Analytical Chemistry, Faculty of Pharmaceutical Sciences, Niigata University of Pharmacy and Applied Life Sciences
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Ohta Shin
Department of Functional Molecular Chemistry, Kyoto Pharmaceutical University
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NAGAI KATSUHIRO
Department of Pharmacy
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