Genetic Association Analysis using Microsatellite Markers in Atopic Dermatitis
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概要
- 論文の詳細を見る
Atopic dermatitis (AD) is presumed to be influenced by genetic and environmental factors. In this study, 54 patients with AD were examined for disease association by the use of 12 microsatellite markers. Several significant associations were recognized in the alleles on chromosome 5, 7 and 11. AD genes were mapped near the FCεRIβ gene (around D11S1314 locus) on chromosome 11, the IL4 gene cluster on chromosome 5 and the TCR γ gene on chromosome 7. This distribution in close proximity to candidate loci for AD is very similar to that of atopic genes, therefore implying that an atopic trait is genetically responsible for the development of AD.
- 東海大学の論文
著者
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Ozawa Akira
Department Of Dermatology Division Of Specialized Clinical Science Tokai University School Of Medici
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Ozawa Akira
東海大学 医学部皮膚科学
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Ozawa Akira
Ntt Advanced Technology Corp.
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Ueyama Y
Dep. Of Pathology Tokai Univ. School Of Medicine
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Ueyama Yoshito
Department Of Pathology Tokai University School Of Medicine
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KATSUYAMA Yoshihiko
Department of Pharmacy, Shinshu University Hospital
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MORITA Eishin
Department of Dermatology, Shimane University Faculty of Medicine
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IIZUKA Mariko
Department of Dermatology, Tokai University School of Medicine
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Ozawa Akira
Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University
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MATSUYAMA Takashi
Department of Dermatology, Tokai University School of Medicine
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UMEZAWA Yoshinori
Department of Dermatology, Division of Specialized Clinical Science, Tokai University School of Medi
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MABUCHI Tomotaka
Department of Dermatology, Tokai University School of Medicine
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KAWADA Hisako
Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine
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INOKO Hidetoshi
Genetic Information, Division of Molecular Life Science, Tokai University School of Medicine
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OTA Masao
Legal Medicine, Shinshu University School of Medicine
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Katsuyama Yoshihiko
Department Of Hospital Pharmacy Shinshu University School Of Medicine
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Ohta Masaaki
Department Of Pediatrics Ehime Prefecturel Imabari Hospital
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Kawada Hisako
Genetic Information Division Of Molecular Life Science Tokai University School Of Medicine
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Morita Eishin
Department Of Dermatology Shimane University Faculty Of Medicine
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Morita Eishin
Department Of Dermatology Hiroshima University School Of Medicine
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Iizuka Mariko
Department Of Dermatology Tokai University School Of Medicine
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Ishihara Mami
Department Of Ophthalmology Yokohama City University School Of Medicine
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Inoko Hidetoshi
Dep. Of Molecular Life Sci. Tokai Univ. School Of Medicine
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Ota Masao
Dep. Of Legal Medicine Shinshu Univ. School Of Medicine
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Umezawa Y
Department Of Dermatology Tokai University School Of Medicine
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Umezawa Yoshinori
Department Of Dermatology Tokai University Of School Of Medicine Boseidai Isehara-city
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Matsuyama T
Department Of Dermatology Tokai University School Of Medicine
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Mabuchi Tomotaka
Department Of Dermatology Tokai University School Of Medicine
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Ueyama Yoshihito
Department Of Pathology Tokai University School Of Medicine
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Katsuyama Yoshihiko
Department of Hospital Pharmacy
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