Leukemoid Reaction in Association with Bone Marrow Necrosis due to Metastatic Prostate Cancer

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概要

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• An 80-year-old man presented to the internist with fever, fatigue and leukocytosis up to 66.8×103/μl. Although a chronic myelogenous leukemia was initially suspected, he was diagnosed as metastatic bone marrow tumor with bone marrow necrosis from primary prostate cancer on the basis of the clinical and pathological findings. The serum concentrations of IL-6 and TNF-α were mildly elevated to 65.0 pg/ml and, 54.0 pg/ml respectively. It is probable that these humoral factors were partially responsible for the leukemoid reaction although other factors induced by the bone marrow necrosis with bone marrow metastasis of prostate cancer are also likely involved.

• 社団法人　日本内科学会の論文

著者

• Ozawa Akira

  Department Of Dermatology Division Of Specialized Clinical Science Tokai University School Of Medici

• FUJITA Shigeru

  First Department of Internal Medicine, Ehime University School of Medicine

• TANJI NOZOMU

  Department of Urology, Ehime University School of Medicine

• YASUKAWA Masaki

  First Department of Internal Medicine, Ehime University

• Ozawa Akira

  Department Of Applied Biological Chemistry College Of Agriculture Osaka Prefecture University

• YAKUSHIJIN YOSHIHIRO

  First Department of Internal Medicine, Ehime University School of Medicine

• Yakushijin Yoshihiro

  First Department Of Internal Medicine Ehime University School Of Medicine

• Fujita Shigeru

  First Department Of Internal Medicine Ehime University School Of Medicine

• Hato Takaaki

  Division Of Blood Transfusion And Cell Therapy Ehime University Graduate School Of Medicine

• Azuma Taichi

  Department Of Bioregulatory Medicine Ehime University Graduate School Of Medicine

• Tanji Nozomu

  Department Of Urology Ehime University Graduate School Of Medicine

• SAKAI Ikuya

  First Department of Internal Medicine, Ehime University Hospital

• Sakai Ikuya

  Department Of Pathophysiology Faculty Of Pharmaceutical Sciences Matsuyama University

• Sakai Ikuya

  First Department Of Internal Medicine Ehime University School Of Medicine

• Sakai I

  Ehime Univ. School Of Medicine Ehime Jpn

• Yasukawa Masaki

  First Department Of Internal Medicine Ehime University School Of Medicine

• AZUMA Taichi

  First Department of Internal Medicine, Ehime University School of Medicine

• MATSUMOTO Takuya

  First Department of Internal Medicine, Ehime University School of Medicine

• WATANABE Akito

  Ehime Prefectural Imabari Hospital

• UCHIDA Naoyuki

  First Department of Internal Medicine, Ehime University School of Medicine

• NARUMI Hirosi

  First Department of Internal Medicine, Ehime University School of Medicine

• YASUKAWA Masaki

  First Department of Internal Medicine, Ehime University School of Medicine

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