Clinical Trial to Investigate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Recombinant Factor VIIa in Japanese Patients With Hemophilia With Inhibitors
スポンサーリンク
概要
- 論文の詳細を見る
- 2001-06-01
著者
-
小嶋 哲人
Department Of Transfusion Medicine Cardiology And Hematology Nagoya University Hospital
-
小嶋 哲人
名古屋大学医学部第一内科
-
小嶋 哲人
名古屋大学 保健
-
Nagase Hideki
Department Of Pediatrics Nara Medical University
-
TAKAMATSU Junki
Department of Transfusion Medicine, Cardiology and Hematology, Nagoya University Hospital
-
Yoshioka Akira
Department of Clinical Research, Maizuru Medical Center
-
Shirahata A
Department Of Pediatrics School Of Medicine University Of Occupational And Environmental Health
-
Shirahata Akira
産業医科大学 医学部小児科学
-
Shirahata Akira
Department Of Pediatrics School Of Medicine University Of Occupational And Environmental Health
-
Saito H
Department Of Hematology Meitetsu Hospital
-
Hiraoka Sakamaki
Department Of Hematology Tokyo Metropolitan Komagome Hospital
-
Kojima Tetsuhito
名古屋市立大学 医学系研究科血液腫瘍内科学
-
Sao Hiroshi
Department Of Hematology Hamamatsu Medical Center
-
KOJIMA Tetsuhito
First Department of Internal Medicine, Nagoya University School of Medicine
-
SAITO Hidehiko
First Department of Internal Medicine, Nagoya University School of Medicine
-
Yoshioka Akira
天理市立病院 小児科
-
Saito H
Nagoya Central Hospital
-
Shirahata A
聖マリアンナ医科大学 医学部医学統計学分野
-
Shirahata Akira
Univ. Occupational And Environmental Health Kitakyushu Jpn
-
SHIMA Midori
Department of Pediatrics, Nara Medical University, Kashihara
-
KAMIYA Tadashi
Japanese Red Cross Aichi Blood Center
-
FUKUTAKE Katsuyuki
Department of Clinical Pathology, Tokyo Medical University
-
ARAI Morio
Department of Clinical Pathology, Tokyo Medical University
-
HANABUSA Hideji
Department of Hematology, Ogikubo Hospital
-
TAGAMI Hisamichi
Department of Hematology, Ogikubo Hospital
-
NAKA Hiroyuki
Department of Pediatrics, Nara Medical University
-
FUJITA Shigeru
First Department of Internal Medicine, Ehime University School of Medicine
-
MINAMOTO Yoko
First Department of Internal Medicine, Ehime University School of Medicine
-
KAMIZONO Junji
Department of Pediatrics, University of Occupational and Environmental Health, Japan
-
Yagi A
Faculty Of Pharmacy And Pharmaceutical Sciences Fukuyama University
-
Arai Morio
Department Of Clinical Pathology Tokyo Medical University
-
Saito Hidehiko
First Department Of Internal Medicine Nagoya University School Of Medicine
-
Kamizono Junji
Department Of Pediatrics School Of Medicine University Of Occupational And Environmental Health
-
Kamizono Junji
Department Of Pediatrics University Of Occupational And Environmental Health Japan
-
NAKAI Hiroaki
Graduate Student of Osaka University, Japan
-
Takamatsu J
Division Of Transfusion Medicine Nagoya University Hospital
-
Takamatsu Junki
Department Of Blood Transfusion Nagoya University School Of Medicine
-
Nakai H
Department Of Pediatrics Nara Medical University
-
Saito H
Nagoya National Hospital
-
Kojima Tetsuhito
First Department First Department Of Internal Medicine Nagoya University School Of Medicine:departme
-
Nakai Hiroaki
Department Of Pediatrics Nara Medical University
-
Shima M
Department Of Pediatrics Nara Medical University
-
Shima Midori
Department Of Pediatrics Nara Medical University
-
Fukutake Katsuyuki
Department Of Laboratory Medicine Tokyo Medical University
-
Fujita Shigeru
First Department Of Internal Medicine Ehime University School Of Medicine
-
Yagi A
Faculty Of Agriculture Shizuoka University
-
Yagi Akihito
Department Of Agricultural Chemistry Shizuoka University
-
Sakka Makiko
Graduate School Of Bioresources Mie Univ.
-
Shibata M
Univ. Tokyo Tokyo Jpn
-
Minamoto Yoko
First Department Of Internal Medicine Ehime University School Of Medicine
-
Yoshioka A
Department Of Pediatrics Nara Medical University
-
Takamatsu Junki
Department Of Blood Transfusion Nagoya University Hospital
-
Suzuki Hideyoshi
Division Of Hematology Tokyo Metropolitan Komagome Hospital
-
Hosaka Naoki
Department Of Pediatrics Nara Medical University
-
Shirahata Akira
Department Of Analytical Chemistry Faculty Of Pharmaceutical Sciences Josai University
-
Hanabusa Hideji
Department Of Hematology Ogikubo Hospital
-
Tagami Hisamichi
Department Of Hematology Ogikubo Hospital
-
Yoshioka Akira
Department Of Applied Biological Chemistry Shizuoka University
-
Fukutake Katsuyuki
Department Of Clinical Pathology Tokyo Medical University
-
Fukuda Kazuyoshi
Department Of Pediatrics Nara Medical University
-
Arai Morio
Department Of Cardiology Tokai University School Of Medicine
-
SHIBATA Masaru
Department of Earth and Space Science Faculty of Science, Osaka University
-
SHIBATA Masaru
Graduate School of Arts and Sciences, University of Tokyo
-
Naka Hiroyuki
Department of Chemistry, Faculty of Technology, Gunma University
関連論文
- 日本人の血栓性素因
- 白血病細胞株を用いた巨核芽球系分化誘導モデルにおけるヒトスフィンゴシンキナーゼ1発現機序の解析
- Long-PCR 法を用いた血液凝固第 VIII 因子 遺伝子の逆位解析
- 尿中HIV抗体検査の臨床的有用性に関する研究-全国11施設による協同研究-
- プロテイン S 欠乏症
- Facial Muscular Atrophy in a Myasthenia Gravis Patient
- 原因不明の出血を初発症状とし,心症状が進行性に出現し死亡した71歳男性
- Activated protein C resistance in the Japanese population due to homozygosity for the factor V R2 haplotype
- Stress-induced PAI-1 expression is suppressed by pitavastatin in vivo
- Definite diagnosis in Japanese patients with protein C deficiency by identification of causative PROC mutations
- Mutational analysis of SOS1 gene in acute myeloid leukemia
- Identification of amino acid residues responsible for von Willebrand factor binding to sulfatide by charged-to-alanine-scanning mutagenesis
- Wilms' tumor 1 message and protein expression in bone marrow failure syndrome and acute leukemia
- Safety and Efficacy of Autologous Progenitor Cell Transplantation for Therapeutic Angiogenesis in Patients With Critical Limb Ischemia
- Mutated RAS Induced PLD1 Gene Expression through Increased Sp1 Trascription Factor
- Recurrent Mutations of Factor XI Gene in Japanese
- シンポジウム3 血栓症への新しいアフローチ血栓症の分子細胞学的基礎-プロテインC, プロテインS欠損症を例として-
- プロテインC-Nagoyaにおける分泌異常の解析
- 日本人血友病BのDNAポリモルフィズムを用いた保因者ならびに出生前遺伝子診断
- 第VIII因子遺伝子逆位解析の重症血友病Aにおける保因者診断, 出生前診断への応用
- ジーンターゲティングを用いた血液凝固制御因子の生体における機能解明 : マウスantithrombinの完全欠損による胎児死亡とsyndecan-4欠損による胎盤迷路層胎児血管の変性
- Recurrent Intramural Hematoma of the Small Intestine in a Severe Hemophilia A Patient with a High Titer of Factor VIII Inhibitor : A Case Report and Review of the Literature
- High Titer of ADAMTS13 Inhibitor Associated with Thrombotic Microangiopathy of the Gut and Skeletal Muscle after Allogeneic Hematopoietic Stem Cell Transplantation
- Shear stress-induced platelet aggregation in various types of von Willebrand disease
- ENHANCED SHEAR STRESS-INDUCED PLATELET AGGREGATION (SIPA) AT CORONARY SINUS IN PATIENTS WITH UNSTABLE ANGINA
- 新生児臍帯血KL-6の基準値
- 新生児、乳児MRSA感染症に対するTDMを利用したアルベカシン投与計画
- ヒトRyudocan分子の精製と生物学的機能解析
- Clinical Trial to Investigate the Pharmacokinetics, Pharmacodynamics, Safety, and Efficacy of Recombinant Factor VIIa in Japanese Patients With Hemophilia With Inhibitors
- Pharmacolinetics, Prophylactic Effects, and Safety of a New Recombinant FVIII Formulated with Sucrose (BAY 14-2222) in Japanese Patients with Hemophilia A
- Cumulative Fraction of Patients with AIDS among Japanese Hemophiliacs Infected with HIV-1
- Intensification of Chemotherapy Using Block Therapies as Consolidation and Reinduction Therapies for Acute Lymphoblastic Leukemia During Childhood
- Noncommutative Minkowski Space and Transcendental Calculus(Field theory, Lattice and Noncommutative space,NONCOMMUTATIVE GEOMETRY AND QUANTUM SPACETIME IN PHYSICS)
- Noncommutative 3-sphere : A model of noncommutative contact algebras Dedicated to Professor Masafumi Okumura for his sixtieth birthday
- A Poincare-Birkhoff-Witt theorem for infinite dimensional Lie algebras
- Analysis for heterozygosity of protein S mRNA: application to genetic screening and family studies in hereditary protein S deficiency
- 生理的抗血栓分子のノックアウトマウス解析
- 教育シンポジウム:がんの遺伝子診断 PCRを用いた遺伝子診断の原理と応用-血友病Bを例にして-
- Identification of intracellular essential factors in platelet granule secretion and aggregation
- Clinical Protocol for Angiogenesis by Intramyocardial Injection of Autologous Bone Marrow Mononuclear Cells in Patients With Severe Coronary Artery Disease : TACT-NAGOYA-HEART
- Prevalence and characterization of hepatitis C virus genotype 4 in Japanese hepatitis C carriers
- Ecthyma gangrenosum combined with multiple perforations of the small intestine associated with Pseudomonas aeruginosa
- Prevalence of hepatitis B virus infection in Japanese patients with HIV
- 先天性凝固阻止因子欠乏症(antithrombin, protein C, protein S 欠損症)
- 血栓性素因部会 : 血栓性素因・プロテインS欠乏症/欠損症をめぐる最近の話題
- 血液凝固亢進状態の抗凝固療法
- Severe hemophilia A in a Japanese female caused by an F8-intron 22 inversion associated with skewed X chromosome inactivation
- Classic Polyarteritis Nodosa Presenting Rare Clinical Manifestations in a Patient with Hemophilia A
- AT/DS併用によるエンドトキシン誘発臓器傷害の改善効果 : Antithrombin/danaparoid sodium の抗凝固薬としての位置付け
- Identification of the regulatory elements of the human von Willebrand factor for binding to platelet GPIb. Importance of structural integrity of the regions flanked by the CYS1272-CYS1458 disulfide bond
- Identification of six novel MYH9 mutations and genotype-phenotype relationships in autosomal dominant macrothrombocytopenia with leukocyte inclusions
- Identification of plasma antibody epitopes and gene abnormalities in Japanese hemophilia a patients with factor VIII inhibitor
- Optimization of the Oxidative Folding Reaction and Disulfide Structure Determination of Multiple-Cystine Peptides
- Modifications Associated with Use of the Benzyloxymethyl Group on Histidine
- Chemical Synthesis of Human β-Defensin (hBD)-1,2,3 and 4 : Optimization for Folding Reduced hBDs into a Native Conformation
- Synthesis and Disulfide Structure Determination of Muscarinic Toxin 3
- Synthesis of Amyloid β-Peptides by Employing a Convergent Solid-Phase Approach Performed in a Mixture of Chloroform and Phenol
- Synthesis and Disulfide Structure Determination of Kurtoxin, a T-type Calcium Channel Blocker
- Synthesis of Prokineticin 2 by Solid-Phase Approach Performed in a Chloroform-Phenol Mixed Solvent
- Synthesis of Human Leptin Employing a Combined Solid-Phase and Solution Approach
- Optimization of Segment Condensation Reactions of Sparingly Soluble Protected Peptides in Chloroform-Phenol Mixed Solvent
- Side Reaction Associated with Use of N^in-Cyclohexyloxy- carbonyl (Hoc) Group for Tryptophans during HF Deprotection
- Synthesis of Muscarinic Toxin 1 and 7 Possessing High Specificity for Muscarinic Acetylcholine Receptor Subtype
- Amino Acid Deletion Products Resulting from Incomplete Deprotecion of the Boc Group during Solid-Phase Peptide Synthesis
- Synthesis of Amyloid β-Peptides in Solution : Chloroform- Phenol Mixed Solvent Is Essential for Segment Condensation of Sparingly Soluble Protected Peptides
- New Powerful Solvent System, A Mixture of Chloroform and Phenol, for Segment Condensation of Sparingly Soluble Protected Petides
- Total Synthesis of Aequorea Green Fluorescent Protein
- Inversions of the Factor VIII Gene in Japanese Patients with Severe Hemophilia A
- Measurement of anti-factor VIII IgG, IgG4 and IgM alloantibodies in previously untreated hemophilia A patients treated with recombinant factor VIII
- Preschool sarcoidosis mimicking juvenile rheumatoid arthritis: The significance of gallium scintigraphy and skin biopsy in the differential diagnosis
- A case of infantile Alexander disease diagnosed by magnetic resonance imaging and genetic analysis
- Highly Conserved Antigenic Structure of the Factor VIII C2 Domain in Some Mammals
- Anti-factor VIII inhibitor alloantibodies recognizing the A2 domain in the human factor VIII heavy chain poorly bind to porcine factor VIII
- A case of West syndrome with atypical massive gray matter heterotopia that is well controlled by ACTH therapy
- Effect of Depolymerized Holothurian Glycosaminoglycan (DHG) on the Activation of Factor VIII and Factor V by Thrombin
- Decline in the HIV-1 Isolation Rate in Japan:A 12-Year Observation
- Intensive Plasma IgG Removal Therapy for Sereve Thrombotic Thrombocytopenic Purpura
- Development of a Strain Measurement Method for Non-Plane Specimens by Means of Computer Picture Processing
- Homozygous type IIC von Willebrand's disease
- von Willebrand Factor-Cleaving Protease and Upshaw-Schulman Syndrome
- Changes in factor VIII binding capacity of von Willebrand factor and factor VIII coagulant activity in two patients with type 2N von Willebrand disease after hemostatic treatment and during pregnancy
- 血友病の遺伝子異常と遺伝子診断
- Simultaneous determination of urinary dialkylphosphate metabolites of organophosphorus pesticides using gas chromatography-mass spectrometry
- Genetic Abnormalities of Bernard-Soulier Syndrome
- Synthesis of Marinostatin, an Ester-Linked Protein Protease Inhibitor from the Marine Bacterium Pseudoalteromonas sagamiensis
- Suppression of Side Reactions during Final Deprotection Employing a Strong Acid
- A Comparative Double-Blind Randomized Trial of Activated Protein C and Unfractionated Heparin in the Treatment of Disseminated Intravascular Coagulation
- 東北地方における血友病インヒビター調査のまとめ
- Virus-Associated Hemophagocytic Syndrome Caused by Pandemic Swine-Origin Influenza A (H1N1) in a Patient After Unrelated Bone Marrow Transplantation
- 抗Xa薬 (凝固制御) -- (抗凝固薬の新展開)
- エストロゲンによるProtein S産生抑制
- ヘパラン硫酸プロテオグリカン・Ryudocanノックアウトマウスの作製・解析
- 日本人の血栓性素因、特にプロテインS欠損症を中心に
- 血栓性素因の病因と病態
- 新規抗凝固薬
- von Willebrand病に合併した未破裂脳動脈瘤に対してコイル塞栓術を行った1例:症例報告
- 新規血栓性素因・アンチトロンビン抵抗性遺伝子異常
- Anticoagulant therapy for hyper coagulation state
- Gene analysis of the congenital thrombophilia –present and future–
- エストロゲンによる Protein S 産生抑制