IMINO ACID AND RELATED ALICYCLIC AMINE LEVELS IN BIOLOGICAL FLUIDS

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概要

• 論文の詳細を見る

• Imino acid and related alicyclic amine concentrations in blood and urine of mammals including humans were concurrently determined by a selected ion monitoring technique. Nanomole levels of proline and pipecolic acid, and pyrrolidine and piperidine as well, were found in human urine. Proline levels but not pipecolic acid levels were higher in blood of humans than in urine. Pyrrolidine and piperidine levels in blood of humans were picomole levels and much lower than those in urine. Similar tendencies were also recognized when these 4 compounds were analyzed using animal blood and urine, although the levels were generally higher in animals than in humans. Significantly high concentrations of the imino acids and the amines were found also in animal semen.

• 社団法人日本薬学会の論文

著者

• NAGATA Junko

  Department of Applied Biological Science, Tokyo Noko University

• Okano Yoshiro

  Department Of Pharmacological Sciences Faculty Of Pharmaceutical Sciences Kumamoto University

• TAKAHAMA Kazuo

  Department of Pharmacological Sciences, Faculty of Pharmaceutical Sciences, Kumamoto University

• MIYATA Takeshi

  Department of Pharmacological Sciences, Faculty of Pharmaceutical Sciences, Kumamoto University

• KADOTA TAKASHI

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• NAKA MASAO

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• IJIMA SAE

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• MATSUDA AKIHIKO

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• IWAMURA HIROYUKI

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• HITOSHI TAIZO

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• 宮田 健

  熊本大学大学院医学薬学研究部薬物活性学分野

• Ijima Sae

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Naka Masao

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Nagata J

  Wildlife Management Laboratory Forestry And Forest Products Research Institute

• Nagata Junko

  Division Of Bioscience Graduate School Of Environmental Earth Science Hokkaido University

• 永田 純子

  森林総合研究所鳥獣管理研究室

• Nagata Junko

  Department Of Applied Biological Science Tokyo Noko University

• Nagata Junko

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Hitoshi Taizo

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Takahama K

  Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Kumamoto University

• Takahama Kazuo

  Department Of Electrical Engineering Faculty Of Engineering Toyo University

• Miyata T

  Department Of Pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Matsuda Akihiko

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Iwamura Hiroyuki

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• Okano Yoshiro

  Department Of Pharmaceutical Care And Clinical Pharmacy Faculty Of Pharmaceutical Sciences Tokushima

• Miyata Takeshi

  Department Of Chemico-pharmacological Sciences Graduate School Of Pharmaceutical Sciences Kumamoto U

• Miyata Takeshi

  Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University

• OKANO Yoshiro

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

• TAKAHAMA Kazuo

  Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University

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