Influence of corticosterone on tracheal mucociliary transport in pigeons.
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概要
- 論文の詳細を見る
The effects of corticosteroids on tracheal mucociliary transport (MCT) were examined in pigeons. Intramuscular administration of corticosterone had no effect at 1.0 mg/kg, while at a larger dose of 5.0 mg/kg, it slightly, but significantly increased the MCT rate. Metyrapone significantly decreased the MCT rate, and the inhibitory action was blocked by 1.0 mg/kg corticosterone. The present study suggested that corticosteroids modulated the mucociliary clearance, especially under some diseases associated with a decreased level of endogenous corticosteroids.
- 公益社団法人 日本薬理学会の論文
著者
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Kai Hirofumi
Department Of Molecular Medicine Faculty Of Pharmaceutical Sciences Kumamoto University
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Yamamoto Satoko
Department Of Agriculture University Of Tokyo Agricultural And Technology
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Miyata Takeshi
Department Of Chemico-pharmacological Sciences Graduate School Of Pharmaceutical Sciences Kumamoto U
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TAKAHAMA Kazuo
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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YAMAMOTO Satoko
Department of Pharmacological Sciences, Faculty of Pharmaceutical Sciences, Kumamoto University
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