MASS FRAGMENTOGRAPHIC ANALYSIS OF PIPERIDINE LEVELS IN TISSUES OF RATS DURING DEVELOPMENT
スポンサーリンク
概要
- 論文の詳細を見る
Piperidine levels in the brain and adrenal gland of rats during development were determined by mass fragmentography with deuterium-labeled piperidine as an internal standard. The levels in both organs showed distinct developmental changes, and two peaks were observed in association with the development of each organ. The initial peaks appeared in the early stage of development, that is, at the 19th day of gestation for the brain and 1 week after birth for the adrenal gland. The second peaks appeared at the age of sexual maturation (10 weeks after birth). The significance of the finding is discussed with respect to a presumed role of piperidine as a neuroendocrine modulator.
- 社団法人日本薬学会の論文
著者
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Okano Yoshiro
Department Of Pharmacological Sciences Faculty Of Pharmaceutical Sciences Kumamoto University
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TAKAHAMA Kazuo
Department of Pharmacological Sciences, Faculty of Pharmaceutical Sciences, Kumamoto University
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MIYATA Takeshi
Department of Pharmacological Sciences, Faculty of Pharmaceutical Sciences, Kumamoto University
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HITOSHI TAIZO
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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FUKUNAGA KOJI
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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KASE YOSHITOSHI
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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宮田 健
熊本大学大学院医学薬学研究部薬物活性学分野
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Fukunaga Koji
Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University
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Hitoshi Taizo
Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University
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Takahama K
Department Of Hygienic Chemistry Faculty Of Pharmaceutical Sciences Kumamoto University
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Takahama Kazuo
Department Of Electrical Engineering Faculty Of Engineering Toyo University
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Okano Yoshiro
Department Of Pharmaceutical Care And Clinical Pharmacy Faculty Of Pharmaceutical Sciences Tokushima
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Miyata Takeshi
Department Of Chemico-pharmacological Sciences Graduate School Of Pharmaceutical Sciences Kumamoto U
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Miyata Takeshi
Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University
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OKANO Yoshiro
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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TAKAHAMA Kazuo
Department of Chemico-Pharmacology, Faculty of Pharmaceutical Sciences, Kumamoto University
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