Treatment of Refractory Crohns Disease by Intensive Granulocyte and Monocyte Adsorption Apheresis: A Report on Two Drug Refractory Cases
スポンサーリンク
概要
- 論文の詳細を見る
Granulocyte and monocyte adsorption apheresis (GMA) is one therapeutic option for induction of remission in patients with inflammatory bowel diseases. Recently intensive GMA (2 sessions per week) was reported to be strikingly better than weekly GMA, both in remission rate and time to remission. Here we report two cases of Crohns disease refractory to weekly GMA who responded to intensive GMA. One patient had not received immunosuppressive therapy while the other had been refractory to combination therapy with infliximab and azathioprine. Intensive GMA induced remission in these 2 patients. Intensive GMA may represent a therapeutic choice for remission induction and maintenance with infliximab.
著者
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Matsuda Akihiko
Department Of Chemico-pharmacology Faculty Of Pharmaceutical Sciences Kumamoto University
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Yamamoto Ryuichi
Department Of Internal Medicine Japan Self Defense Forces Fukuoka Hospital
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Yakabi Koji
Department Of Gastroenterology And Hepatology Saitama Medical Center Saitama Medical University
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Kato Shingo
Department Of Gastroenterology And Hepatology Saitama Medical Center Saitama Medical University
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Takabayashi Hidehiko
Department Of Gastroenterology And Hepatology Saitama Medical Center Saitama Medical University
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Yakabi Koji
Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Japan
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Kani Kazuhito
Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Japan
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Ogawa Tomonari
Department of Nephrology and Hypertension, Saitama Medical Center, Saitama Medical University, Japan
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Matsuda Akihiko
Department of Nephrology and Hypertension, Saitama Medical Center, Saitama Medical University, Japan
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Kato Shingo
Department of Cardiology, Kanagawa Cardiovascular and Respiratory Center
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Kato Shingo
Department of Gastroenterology and Hepatology, Saitama Medical Center, Saitama Medical University, Japan
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