Marine Natural Products. XXVII. Distribution of Lanostane-Type Triterpene Oligoglycosides in Ten Kinds of Okinawan Sea Cucumbers

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概要

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• Triterpene-oligoglycoside constituents in ten sea cucumber species inhabiting Okinawan coral reefs were investigated. Several antifungal oligoglycosides were isolated from six species [stichlorosides A_1 (15), A_2 (16), B_1 (17), B_2 (18), C_1 (19), and C_2 (20) from Thelonota ananas (baika-namako in Japanese) and Stichopus hermanni; 15,17,and 19 from Thelonota anax; bivittosides C (13) and D (14) from Bohadschia argus (janome-namako); holothurin A (6) from Holothuria edulis (akamishikiri); and 6 and echinoside A (10) from Bohadschia graeffei (kurote-namako)]. Furthermore, several oligoglycosides were isolated in their desulfated forms from four species [6 and 10 from Holothuria axiologa; holothurin B (4), 6,echinoside B (8), and 10 from Holothuria atra (kuro-namako); 6,10,and 24-dehydroechinoside A (24) from Holothuria scabra (haneji-namako); and 8,10,24-dehydroechinoside B (22), and 24 from Actinopyga mauritiana (kuriiro-namako)]. 24-Dehydroechinoside B (22) is a new lanostane-type triterpene oligoglycoside.

• 公益社団法人日本薬学会の論文
• 1991-09-25

著者

• 北川 勲

  Faculty of Pharmaceutical Sciences, Osaka University

• 小林 資正

  Faculty of Pharmaceutical Sciences, Osaka University

• 堀 学

  Faculty of Pharmaceutical Sciences, Osaka University

• 北川 勲

  Faculty Of Pharmaceutical Sciences Osaka University

• 鈴木 茂樹

  Faculty Of Pharmaceutical Sciences Osaka University

• 安澤 亨

  Faculty of Pharmaceutical Sciences, Osaka University

• Kobayashi M

  Fujisawa Pharmaceutical Co. Ltd. :(peresent Address)fujisawa Research Insitute Of America Inc. North

• 堀 学

  New Drug Research Laboratories, Kanebo Ltd.,

• 菅 久美子

  Faculty of Pharmaceutical Sciences, Osaka University

• 松井 松太郎

  Faculty of Pharmaceutical Sciences, Osaka University

• Kobayashi M

  Faculty Of Pharmaceutical Sciences Osaka University

• 堀 学

  New Drug Research Laboratories Kanebo Ltd.

• 安澤 亨

  Faculty Of Pharmaceutical Sciences Osaka University

• 松井 松太郎

  Faculty Of Pharmaceutical Sciences Osaka University

• 菅 久美子

  Faculty Of Pharmaceutical Sciences Osaka University

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