Synthssis of Saframycins. II. : Preparations and Reactions of N-Methyl-2,5-piperazinediones
スポンサーリンク
概要
- 論文の詳細を見る
An efficient synthesis of 4-methyl-3-(2,4,5-trimethoxy-3-methylphenylmethyl)-2,5-piperazinedione 5 and 1-methyl-3-(2,4,5-trimethoxy-3-methylphenylmethyl)-2,5-piperazinedione 10 from (Z)-1-acetyl-3-(2,4,5-trimethoxy-3-methylphenylmethyl)-2,5-piperazinedione 2 is described.The 1-methyl-2,5-piperazinedione 10 is shown to be a useful intermediate for preparation of the 1,5-imino-3-benzazocine derivative 16,which is the skeleton of the "right half" of saframycins.
- 社団法人日本薬学会の論文
- 1988-07-25
著者
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齋藤 直樹
Meiji Pharmaceutical University
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久保 陽徳
明治薬科大学
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久保 陽徳
Meiji College of Pharmacy
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大和 秀一
Meiji College of Pharmacy
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山内 玲子
Meiji College of Pharmacy
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蛭間 和美
Meiji College of Pharmacy
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井上 玲
Meiji College of Pharmacy
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Kubo Akinori
Graduate School Of Pharmaceutical Sciences Meiji Pharmaceutical University
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