Synthesis of 5,6-, 5,8- and 7,8-Isoquinolinediones from the Corresponding Isoquinolinols and Dimethoxyisoquinolines

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概要

• 論文の詳細を見る

• 5,8-Isopuinolinediones (12,18,25), 7,8-isoquinolinediones (14,19) and 5,6-isoquinolinediones (26) were synthesized by oxidative demethylation of the corresponding dimethoxyisoquinolines with cerium(IV) ammonium nitrate or silver(II) oxide. 8-Dialkylamino-5,6-isoquinolinediones (31) and 3,5-bis(dialkylamino)-7,8-isoquinolinediones (33) were prepared by copper(II)-catalyzed oxidation of the corresponding isoquinolinols with secondary amines. 5,8-Isoquinolinediones (29,34,40) were also prepared.

• 社団法人日本薬学会の論文
• 1991-09-25

著者

• 久保 陽徳

  明治薬科大学

• 久保 陽徳

  Meiji College of Pharmacy

• 北原 嘉泰

  Meiji College of Pharmacy

• 北原 嘉泰

  明治薬科大学

• 中原 伸輔

  Meiji College of Pharmacy

• 赤澤 学

  Meiji College Of Pharmacy

• 中井 龍也

  Meiji College of Pharmacy

• 清水 昌郎

  Meiji College of Pharmacy

• Kubo Akinori

  Graduate School Of Pharmaceutical Sciences Meiji Pharmaceutical University

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