Reactions of 2-Hydroxytryptophol : Results of Strong Acid and Alkaline Treatments of 2-Hydroxytryptophol
スポンサーリンク
概要
- 論文の詳細を見る
Upon being warmed at 90℃ in trifluoromethanesulfonic acid for 42-78 h, 2-hydroxytryptophol (4a) gave 3-ethylideneoxidoles (E-and Z-form) (5a), while 3-methyl-(4b) or 3-ethyl-2-hydroxytryptophol (4c) gave the corresponding 3-alkylideneoxindoles (5b, 5c) and 3,4-dialkylcarbostyrils (6_<1-b, c>, 6_<H-c>). On tosylation in pyridine, 4a gave spiro-(3)-cyclopropane-(8) and 3-chloroethyl-oxindole (10), and the corresponding tosylate (7a), but 4b and 4c gave only the corresponding tosylates (7b, 7c). The tosylate 7a and the chloroethyl compound 10 reacted in alkaline ethanol to afford the spiro compound 8,whereas the tosylates 7b, 7c gave 2-ethoxy-3-methyl (or ethyl)-3-hydroxyethylindolenines (9b, 9c) under the same conditions.
- 公益社団法人日本薬学会の論文
- 1983-09-25
著者
関連論文
- Synthesis of 5,6-, 5,8- and 7,8-Isoquinolinediones from the Corresponding Isoquinolinols and Dimethoxyisoquinolines
- Reactions of Indole Related Compounds. III. (E) and (Z)-2-Oxoindolin-3-ethylidenes
- Synthesis of 8-Amino-5,6-quinolinediones from 6-Quinolinols and 5,6-Dimethoxyquinolines
- Synthetic Approach to Diterpene Alkaloids. II. Unusual Reaction of Angular Nitromethyl Group with Diazomethane to Give Aldoxime(Organic,Chemical)
- Synthetic Approach to Diterpene Alkaloids : Construction of the Bridged Azabicyclic Ring System of Kobusine
- Reactions of 2-Hydroxytryptophol. II. : Solvolysis of 3-Substituted-2-hydroxytryptophol and N-Methyl Derivatives with Alcoholic Alkali
- Reactions of 2-Hydroxytryptophol : Results of Strong Acid and Alkaline Treatments of 2-Hydroxytryptophol
- 「かぎかづら」のアルカロイド研究(第21報)リンコフィリンとコリノキセインの分離について
- 2-ヒドロキシトリプトフォールの合成
- Studies on Uncaria Alkaloid. XX. Structure of Rhynchophylline. (5). Structure of Rhynchophylline and Isorhynchophylline.
- Studies on Uncaria Alkaloid. XIX. On Mitraphylline.
- Studies on Uncaria Alkaloid. XVIII. Structure of Uncarine. (13). Structure of Uncarine-A and Uncarine-B.
- Synthese von Guanidinverbindungen des Diphenylathers. III. Versuche mit Methylguanidinderivaten. (2). Pyrimidinverbindungen.