Studies on Uncaria Alkaloid. XX. Structure of Rhynchophylline. (5). Structure of Rhynchophylline and Isorhynchophylline.

スポンサーリンク

概要

• 論文の詳細を見る

• Reduction of rhynchophylline with lithium aluminum hydride afforded an indoline derivative, which indicated the 3-position of the oxindole ring in its molecule is a spiro type, and the formula (III) was forwarded for rhynchophylline in analogy with uncarine. Rhynchophylline and isorhynchophylline are considered to be 4-epimers, similar to uncarine-A and -B, because their compositions are the same, their ultraviolet and infrared spectra are in close similarity, and the two easily undergo isomerization. From the measurement of pK, the formula (V) for rhynchophylline and (IV) for isorhynchophylline are proposed.

• 公益社団法人日本薬学会の論文
• 1958-06-20

著者

• 野副 利一

  Meiji College of Pharmacy

• 野副 利一

  ITSUU Laboratory

関連論文

• Reactions of Indole Related Compounds. III. (E) and (Z)-2-Oxoindolin-3-ethylidenes
• Reactions of 2-Hydroxytryptophol. II. : Solvolysis of 3-Substituted-2-hydroxytryptophol and N-Methyl Derivatives with Alcoholic Alkali
• Reactions of 2-Hydroxytryptophol : Results of Strong Acid and Alkaline Treatments of 2-Hydroxytryptophol
• Studies on Uncaria Alkaloid. XX. Structure of Rhynchophylline. (5). Structure of Rhynchophylline and Isorhynchophylline.
• Studies on Uncaria Alkaloid. XIX. On Mitraphylline.
• Studies on Uncaria Alkaloid. XVIII. Structure of Uncarine. (13). Structure of Uncarine-A and Uncarine-B.

スポンサーリンク