The Principles of Tetragonia tetragonoides having Anti-ulcerogenic Activity. II. Isolation and Structure of Cerebrosides
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概要
- 論文の詳細を見る
Compound B_1 (tentative name), isolated from Tetragonia tetragonoides as a principle with anti-ulcerogenic activity, was determined to be a mixture of geometrical isomers of 1-O-β-D-glucopyranosyl-2-N-2'-hydroxypalmitoyl-sphinga-4,8-dienine on the basis of chemical and spectral evidence. By repeated chromatography, compound B_1 was separated into compounds B_<1-a> (major) and B_<1-b> (minor), which were found to be the 4-trans-8-trans and 4-trans-8-cis isomers, respectively. Several cerebrosides and glycolipids from various biological sources were examined for protective activity against the ulcer formation in mice under restraint and water immersion condition.
- 社団法人日本薬学会の論文
- 1983-07-25
著者
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山崎 幹夫
Research Institute for Chemobiodynamics, Chiba University
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山崎 幹夫
Faculty of Pharmaceutical Sciences, Chiba University
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奥山 恵美
千葉大院薬
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奥山 恵美
Research Institute for Chemobiodynamics, Chiba University
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奥山 恵美
千葉大学 院薬
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