Structure Determination of Violaceol-I and -II, New Fungal Metabolites from a Strain of Emericella violacea
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概要
- 論文の詳細を見る
A toxic metabolite, violaceol, which was isolated from the fungus, E. violacea, was found to be a mixture of two isomers. Violaceol-I (3) and -II (4) were isolated as tetraacetates through acetylation and preparative thin layer chromatography. The structures of violaceol-I and -II were determined as shown in Fig. 1 and 2,mainly by the analysis of the ^1H- and ^<13>C-nuclear magnetic resonance spectral data, especially the ^<13>C-^1H indirect spin coupling constants. Violaceols were lethal to mice and exhibited weak antimicrobial activity.
- 公益社団法人日本薬学会の論文
- 1982-02-25
著者
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山崎 幹夫
Research Institute for Chemobiodynamics, Chiba University
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山崎 幹夫
千葉大学
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前林 行雄
Research Institute for Chemobiodynamics, Chiba University
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前林 行雄
Faculty Of Pharmaceutical Sciences Chiba University
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山田 美紀子
Hoshi College of Pharmacy
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