Thio-analogues of 6-Substituted 1,3-Dimethyl-7-azalumazine (Fervenulin) and 7-Substituted 1,3-Dimethyl-6-azalumazine (Isofervenulin)

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概要

• 論文の詳細を見る

• 1,3-Dimethyl-4-thio-7-azalumazine derivatives (5-thiofervenulins) and 1,3-dimethyl-4-thio-6-azalumazine derivatives (5-thioisofervenulins) were synthesized by the thiation of 1,3-dimethyl-7-azalumazine derivatives (fervenulins) and 1,3-dimethyl-6-azalumazine derivatives (isofervenulins). The 1,3-dimethyl-4-thio-6-azalumazines were converted into theophyllines by treatment with sodium dithionite in formic acid. These thio-azalumazines displayed low antibacterial activities in vitro.

• 公益社団法人日本薬学会の論文
• 1973-05-25

著者

• 米田 文郎

  Faculty Of Pharmaceutical Sciences Kyoto University

• 佐久間 義治

  Faculty of Pharmaceutical Sciences, Kumamoto University

• 西垣 貞男

  Pharmaceutical Institute School Of Medicine Keio University

• 西垣 貞雄

  Pharmaceutical Institute School Of Medicine Keio University

• 上野 猷子

  Pharmaceutical Institute, Keio University

• 上野 猷子

  Pharmaceutical Institute Keio University

• 佐久間 義治

  Faculty Of Pharmaceutical Sciences Kumamoto University

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