The Mechanism of the Formation of an Abnormal Product in the Chichibabin Reaction of Quinoline (Studies on the Syntheses of Heterocyclic Compounds. CCLIII)

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概要

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• The Chichibabin reaction of quinoline (I) in dimethylaniline with sodium amide was carried out, to give a mixture of 2-aminoquinoline (II) and unexpected 2-amino-3,4-dihydroquinoline (III). Furthermore, the mechanism of the formation of III was revealed by comparison of the product obtained from 2-deuterioquinoline by the same method as above from the point of nuclear magnetic resonance and mass spectra.

• 公益社団法人日本薬学会の論文
• 1968-09-25

著者

• 根本 英雄

  Pharmaceutical Institute, Tohoku University School of Medicine

• 根本 英雄

  東北大薬

• 亀谷 哲治

  Pharmaceutical Institute Medical Faculty University Of Osaka

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