ストレプトスライシン抗生物質の産生に及ぼすグルコースの阻害効果 : ストレプトスライシン抗生物質S-2産生に関する生化学的研究(第1報)

概要

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A newly isolated streptomycete S-2 which was identified as Streptomyces lavendulae (Waksman and Curtis) Waksman and Henrici produced a streptothricin antibiotic having high content of β-lysine.Production of the antibiotic S-2 was remarkably inhibitted by the presence of glucose in Waksman medium, although glucose was the best carbon source for the growth of the isolated streptomycete S-2. The inhibiting effect of 1% glucose on antibiotic S-2 formation disappeared on addition of amino acids mixture.On the other hand, it was of interest to note that the strong inhibitory effect was not found in synthetic medium containing amino acid mixture as nitrogen source.
社団法人日本生物工学会の論文
1976-11-25